KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD4
All Species:
23.94
Human Site:
Y664
Identified Species:
43.89
UniProt:
Q14839
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14839
NP_001264.2
1912
217991
Y664
E
D
V
E
I
Q
D
Y
D
L
F
K
Q
S
Y
Chimpanzee
Pan troglodytes
XP_001162478
1893
216259
Y645
E
D
V
E
I
Q
D
Y
D
L
F
K
Q
S
Y
Rhesus Macaque
Macaca mulatta
XP_001107319
1912
217912
Y664
E
D
V
E
I
Q
D
Y
D
L
F
K
Q
S
Y
Dog
Lupus familis
XP_534909
1912
217966
Y664
E
D
V
E
I
Q
D
Y
D
L
F
K
Q
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q6PDQ2
1915
217732
Y657
E
D
V
E
I
Q
D
Y
D
L
F
K
Q
S
Y
Rat
Rattus norvegicus
Q9JIX5
2581
290674
H734
D
R
I
L
D
E
S
H
S
V
D
K
D
N
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q06A37
3011
338194
K851
V
E
E
L
D
K
D
K
R
I
Q
Q
K
I
K
Frog
Xenopus laevis
NP_001080504
1893
214670
Y655
E
E
S
D
I
Q
D
Y
D
I
Y
K
Q
G
Y
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
H770
D
R
I
L
D
E
S
H
S
V
D
K
D
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O97159
1982
224182
L654
E
G
D
D
I
Q
G
L
R
Q
A
I
D
Y
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
Y602
K
I
D
I
L
K
K
Y
E
V
Q
P
D
F
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
E338
T
L
R
N
W
E
R
E
F
A
T
W
A
P
Q
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
R422
I
S
W
L
I
F
A
R
R
Q
N
G
P
H
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
99.7
99.3
N.A.
98.1
22.8
N.A.
N.A.
22.6
84.5
23.1
N.A.
55.7
N.A.
43.2
N.A.
Protein Similarity:
100
98.9
99.7
99.5
N.A.
98.6
36.9
N.A.
N.A.
35
90.5
38.4
N.A.
69.5
N.A.
59.2
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
N.A.
6.6
60
6.6
N.A.
26.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
46.6
N.A.
N.A.
40
86.6
46.6
N.A.
33.3
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.6
26.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.4
41.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
8
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
39
16
16
24
0
54
0
47
0
16
0
31
0
0
% D
% Glu:
54
16
8
39
0
24
0
8
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
8
0
39
0
0
8
0
% F
% Gly:
0
8
0
0
0
0
8
0
0
0
0
8
0
8
16
% G
% His:
0
0
0
0
0
0
0
16
0
0
0
0
0
8
0
% H
% Ile:
8
8
16
8
62
0
0
0
0
16
0
8
0
8
16
% I
% Lys:
8
0
0
0
0
16
8
8
0
0
0
62
8
0
8
% K
% Leu:
0
8
0
31
8
0
0
8
0
39
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
8
0
0
16
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
8
8
0
% P
% Gln:
0
0
0
0
0
54
0
0
0
16
16
8
47
0
8
% Q
% Arg:
0
16
8
0
0
0
8
8
24
0
0
0
0
0
0
% R
% Ser:
0
8
8
0
0
0
16
0
16
0
0
0
0
39
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% T
% Val:
8
0
39
0
0
0
0
0
0
24
0
0
0
0
0
% V
% Trp:
0
0
8
0
8
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
8
0
0
8
54
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _