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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LASP1 All Species: 28.48
Human Site: T63 Identified Species: 48.21
UniProt: Q14847 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14847 NP_006139.1 261 29717 T63 H Y P K Q S F T M V A D T P E
Chimpanzee Pan troglodytes XP_511445 391 42950 T193 H Y P K Q S F T M V A D T P E
Rhesus Macaque Macaca mulatta XP_001085111 261 29741 T63 H Y P K Q S F T M V A D T P E
Dog Lupus familis XP_851714 257 29048 K59 Y C N A H Y P K Q S F T M V A
Cat Felis silvestris
Mouse Mus musculus Q61792 263 29976 T63 H Y P K Q S F T M V A D T P E
Rat Rattus norvegicus Q99MZ8 263 29952 T63 H Y P K Q S F T M V A D T P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516545 118 13511
Chicken Gallus gallus Q01406 563 63311 K275 H E S Q K D Y K S G F G G K F
Frog Xenopus laevis Q6GM14 376 42749 N177 I K R V G K E N F W A K A E K
Zebra Danio Brachydanio rerio NP_997801 234 26681 M37 F S C E V C K M T L N M K N Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8I7C3 657 74228 T63 H I P K A K A T A I A D T P E
Honey Bee Apis mellifera XP_001121584 320 35562 T63 H I P K V K A T T M A E T P E
Nematode Worm Caenorhab. elegans P34416 335 37006 S65 H Y P K T V A S V M A D T P E
Sea Urchin Strong. purpuratus XP_797085 249 27176 Y52 K G Y N K L P Y C N T H Y P T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 66.7 98.4 94.6 N.A. 95.4 96.1 N.A. 41.7 21.3 21.8 68.5 N.A. 23.1 42.1 37.3 50.1
Protein Similarity: 100 66.7 99.2 95.7 N.A. 97.3 97.3 N.A. 43.6 30.5 38 75.4 N.A. 30.4 53.4 51 60.5
P-Site Identity: 100 100 100 0 N.A. 100 100 N.A. 0 6.6 6.6 0 N.A. 60 53.3 60 6.6
P-Site Similarity: 100 100 100 6.6 N.A. 100 100 N.A. 0 26.6 13.3 13.3 N.A. 66.6 66.6 80 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 0 22 0 8 0 65 0 8 0 8 % A
% Cys: 0 8 8 0 0 8 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 0 0 0 50 0 0 0 % D
% Glu: 0 8 0 8 0 0 8 0 0 0 0 8 0 8 58 % E
% Phe: 8 0 0 0 0 0 36 0 8 0 15 0 0 0 8 % F
% Gly: 0 8 0 0 8 0 0 0 0 8 0 8 8 0 0 % G
% His: 65 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 8 15 0 0 0 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 8 8 0 58 15 22 8 15 0 0 0 8 8 8 8 % K
% Leu: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 8 36 15 0 8 8 0 0 % M
% Asn: 0 0 8 8 0 0 0 8 0 8 8 0 0 8 0 % N
% Pro: 0 0 58 0 0 0 15 0 0 0 0 0 0 65 0 % P
% Gln: 0 0 0 8 36 0 0 0 8 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 8 8 0 0 36 0 8 8 8 0 0 0 0 0 % S
% Thr: 0 0 0 0 8 0 0 50 15 0 8 8 58 0 8 % T
% Val: 0 0 0 8 15 8 0 0 8 36 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 8 43 8 0 0 8 8 8 0 0 0 0 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _