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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LASP1
All Species:
20
Human Site:
Y122
Identified Species:
33.85
UniProt:
Q14847
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14847
NP_006139.1
261
29717
Y122
D
Q
I
S
N
I
K
Y
H
E
E
F
E
K
S
Chimpanzee
Pan troglodytes
XP_511445
391
42950
Y252
D
Q
I
S
N
I
K
Y
H
E
E
F
E
K
S
Rhesus Macaque
Macaca mulatta
XP_001085111
261
29741
Y122
D
Q
I
S
N
I
K
Y
H
E
E
F
E
K
S
Dog
Lupus familis
XP_851714
257
29048
S118
K
K
T
Q
D
Q
I
S
N
I
K
Y
H
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61792
263
29976
Y122
D
Q
I
S
N
I
K
Y
H
E
E
F
E
K
S
Rat
Rattus norvegicus
Q99MZ8
263
29952
Y122
D
Q
I
S
N
I
K
Y
H
E
E
F
E
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516545
118
13511
Chicken
Gallus gallus
Q01406
563
63311
E334
D
K
N
A
A
T
F
E
D
I
E
K
P
T
S
Frog
Xenopus laevis
Q6GM14
376
42749
Q236
E
I
D
G
H
R
K
Q
Q
E
E
V
E
K
Q
Zebra Danio
Brachydanio rerio
NP_997801
234
26681
K96
E
F
E
K
N
K
G
K
G
F
S
V
V
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8I7C3
657
74228
H122
H
I
S
N
V
A
Y
H
G
D
L
E
K
K
A
Honey Bee
Apis mellifera
XP_001121584
320
35562
H122
I
I
S
N
V
A
Y
H
G
E
L
Q
K
K
A
Nematode Worm
Caenorhab. elegans
P34416
335
37006
H124
V
Q
S
N
V
S
Y
H
G
V
L
D
Q
K
A
Sea Urchin
Strong. purpuratus
XP_797085
249
27176
K111
P
E
S
L
R
L
K
K
N
T
H
Q
A
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
66.7
98.4
94.6
N.A.
95.4
96.1
N.A.
41.7
21.3
21.8
68.5
N.A.
23.1
42.1
37.3
50.1
Protein Similarity:
100
66.7
99.2
95.7
N.A.
97.3
97.3
N.A.
43.6
30.5
38
75.4
N.A.
30.4
53.4
51
60.5
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
0
20
33.3
6.6
N.A.
6.6
13.3
13.3
6.6
P-Site Similarity:
100
100
100
40
N.A.
100
100
N.A.
0
33.3
46.6
13.3
N.A.
40
40
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
15
0
0
0
0
0
0
8
8
22
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
43
0
8
0
8
0
0
0
8
8
0
8
0
0
15
% D
% Glu:
15
8
8
0
0
0
0
8
0
50
50
8
43
8
8
% E
% Phe:
0
8
0
0
0
0
8
0
0
8
0
36
0
0
0
% F
% Gly:
0
0
0
8
0
0
8
0
29
0
0
0
0
0
0
% G
% His:
8
0
0
0
8
0
0
22
36
0
8
0
8
0
0
% H
% Ile:
8
22
36
0
0
36
8
0
0
15
0
0
0
0
0
% I
% Lys:
8
15
0
8
0
8
50
15
0
0
8
8
15
65
0
% K
% Leu:
0
0
0
8
0
8
0
0
0
0
22
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
22
43
0
0
0
15
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
43
0
8
0
8
0
8
8
0
0
15
8
0
8
% Q
% Arg:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
29
36
0
8
0
8
0
0
8
0
0
8
43
% S
% Thr:
0
0
8
0
0
8
0
0
0
8
0
0
0
8
0
% T
% Val:
8
0
0
0
22
0
0
0
0
8
0
15
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
22
36
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _