KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LASP1
All Species:
12.73
Human Site:
Y186
Identified Species:
21.54
UniProt:
Q14847
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14847
NP_006139.1
261
29717
Y186
V
A
Q
S
Y
G
G
Y
K
E
P
A
A
P
V
Chimpanzee
Pan troglodytes
XP_511445
391
42950
Y316
V
A
Q
S
Y
G
G
Y
K
E
P
A
A
P
V
Rhesus Macaque
Macaca mulatta
XP_001085111
261
29741
Y186
V
A
Q
S
Y
G
G
Y
K
E
P
A
A
P
V
Dog
Lupus familis
XP_851714
257
29048
G182
Q
V
A
Q
S
Y
G
G
Y
K
E
P
A
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61792
263
29976
G186
Q
Q
M
T
S
S
Y
G
G
Y
K
E
P
A
A
Rat
Rattus norvegicus
Q99MZ8
263
29952
G186
Q
Q
V
T
P
S
Y
G
G
Y
K
E
P
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516545
118
13511
Y44
M
T
L
N
M
K
N
Y
K
G
Y
E
K
K
P
Chicken
Gallus gallus
Q01406
563
63311
R398
Q
E
Q
E
E
A
R
R
K
L
E
E
Q
A
K
Frog
Xenopus laevis
Q6GM14
376
42749
Y300
A
T
E
N
Q
N
I
Y
E
D
T
P
Q
E
D
Zebra Danio
Brachydanio rerio
NP_997801
234
26681
Y160
A
A
S
Q
N
Y
H
Y
E
P
E
P
V
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8I7C3
657
74228
Q186
Q
Q
Q
Q
L
Q
H
Q
Q
Q
Q
Q
Y
Q
Q
Honey Bee
Apis mellifera
XP_001121584
320
35562
D186
P
G
R
I
A
D
Y
D
P
L
S
E
A
R
P
Nematode Worm
Caenorhab. elegans
P34416
335
37006
K188
A
V
S
P
T
P
Q
K
S
I
G
S
I
A
D
Sea Urchin
Strong. purpuratus
XP_797085
249
27176
Q175
Q
P
A
A
P
V
Q
Q
P
P
P
Q
Q
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
66.7
98.4
94.6
N.A.
95.4
96.1
N.A.
41.7
21.3
21.8
68.5
N.A.
23.1
42.1
37.3
50.1
Protein Similarity:
100
66.7
99.2
95.7
N.A.
97.3
97.3
N.A.
43.6
30.5
38
75.4
N.A.
30.4
53.4
51
60.5
P-Site Identity:
100
100
100
13.3
N.A.
0
0
N.A.
13.3
13.3
6.6
13.3
N.A.
6.6
6.6
0
6.6
P-Site Similarity:
100
100
100
20
N.A.
6.6
6.6
N.A.
26.6
13.3
33.3
20
N.A.
20
13.3
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
29
15
8
8
8
0
0
0
0
0
22
36
36
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
8
0
8
0
0
0
0
15
% D
% Glu:
0
8
8
8
8
0
0
0
15
22
22
36
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
22
29
22
15
8
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
8
0
0
8
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
8
0
8
36
8
15
0
8
8
8
% K
% Leu:
0
0
8
0
8
0
0
0
0
15
0
0
0
8
0
% L
% Met:
8
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
15
8
8
8
0
0
0
0
0
0
0
0
% N
% Pro:
8
8
0
8
15
8
0
0
15
15
29
22
15
22
29
% P
% Gln:
43
22
36
22
8
8
15
15
8
8
8
15
22
8
8
% Q
% Arg:
0
0
8
0
0
0
8
8
0
0
0
0
0
15
0
% R
% Ser:
0
0
15
22
15
15
0
0
8
0
8
8
0
0
8
% S
% Thr:
0
15
0
15
8
0
0
0
0
0
8
0
0
0
0
% T
% Val:
22
15
8
0
0
8
0
0
0
0
0
0
8
0
22
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
22
15
22
43
8
15
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _