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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POU6F1 All Species: 46.67
Human Site: S181 Identified Species: 78.97
UniProt: Q14863 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14863 NP_002693.3 301 32645 S181 A T E G P A Y S Q S A I C R F
Chimpanzee Pan troglodytes XP_001149146 579 59816 S459 A T E G P A Y S Q S A I C R F
Rhesus Macaque Macaca mulatta Q28503 291 32940 F180 F E N L Q L S F K N A C K L K
Dog Lupus familis XP_543666 643 66150 S523 A T E G P A Y S Q S A I C R F
Cat Felis silvestris
Mouse Mus musculus Q07916 301 32833 S181 A T E G P A Y S Q S A I C R F
Rat Rattus norvegicus P56223 301 32683 S181 A T E G P A Y S Q S A I C R F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512107 672 71126 S499 A T E G P A Y S Q S A I C R H
Chicken Gallus gallus Q9YGL7 363 40431 S237 A V H G S E F S Q T T I C R F
Frog Xenopus laevis Q91989 426 47235 S244 I L Y G K M F S Q T T I C R F
Zebra Danio Brachydanio rerio P31367 610 63106 S490 A T E G P A Y S Q S A I C R F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P16241 427 45909 S254 T L Y G N V F S Q T T I C R F
Honey Bee Apis mellifera XP_391982 671 72301 S551 V T E G P A Y S Q S A I C R F
Nematode Worm Caenorhab. elegans P20268 380 42556 S229 T L Y G N I F S Q T T I C R F
Sea Urchin Strong. purpuratus XP_785865 586 60667 S443 Q S E G P A Y S Q S A I C R F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.9 34.2 46 N.A. 95.3 96.3 N.A. 31.9 33.6 28.6 39.5 N.A. 24.8 29.8 30 33.9
Protein Similarity: 100 51.9 48.1 46.3 N.A. 96.6 97 N.A. 37.6 47.6 40.8 43.9 N.A. 37.7 37.4 42.6 42.1
P-Site Identity: 100 100 6.6 100 N.A. 100 100 N.A. 93.3 53.3 46.6 100 N.A. 46.6 93.3 46.6 86.6
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. 93.3 66.6 60 100 N.A. 60 93.3 60 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 58 0 0 0 0 65 0 0 0 0 72 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 93 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 8 65 0 0 8 0 0 0 0 0 0 0 0 0 % E
% Phe: 8 0 0 0 0 0 29 8 0 0 0 0 0 0 86 % F
% Gly: 0 0 0 93 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 8 0 0 0 0 8 0 0 0 0 0 93 0 0 0 % I
% Lys: 0 0 0 0 8 0 0 0 8 0 0 0 8 0 8 % K
% Leu: 0 22 0 8 0 8 0 0 0 0 0 0 0 8 0 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 15 0 0 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 65 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 8 0 0 0 93 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 93 0 % R
% Ser: 0 8 0 0 8 0 8 93 0 65 0 0 0 0 0 % S
% Thr: 15 58 0 0 0 0 0 0 0 29 29 0 0 0 0 % T
% Val: 8 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 22 0 0 0 65 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _