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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POU6F1 All Species: 19.39
Human Site: S78 Identified Species: 32.82
UniProt: Q14863 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14863 NP_002693.3 301 32645 S78 R K P S T P E S P A K S E V Q
Chimpanzee Pan troglodytes XP_001149146 579 59816 S356 R K P S T P E S P A K S E V Q
Rhesus Macaque Macaca mulatta Q28503 291 32940 P82 T L V F Y K F P D H T L S H G
Dog Lupus familis XP_543666 643 66150 S420 R K A S T P E S P A K S E V Q
Cat Felis silvestris
Mouse Mus musculus Q07916 301 32833 S78 R K P N T P E S P A K S E V Q
Rat Rattus norvegicus P56223 301 32683 S78 R K P S T P E S P A K S E V Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512107 672 71126 L388 Q G I T L S P L K P G Q Q L H
Chicken Gallus gallus Q9YGL7 363 40431 L142 Q S S L T P C L Y K F P E H A
Frog Xenopus laevis Q91989 426 47235 A83 H F Q I S N Q A A S N S S G D
Zebra Danio Brachydanio rerio P31367 610 63106 V379 A I P S T A S V L P K A T V P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P16241 427 45909 L101 Q T H H T H H L P A A A A V A
Honey Bee Apis mellifera XP_391982 671 72301 T330 Q P Q N M L N T P T S N G E F
Nematode Worm Caenorhab. elegans P20268 380 42556 D90 H F M L P Q H D W A Y P H L A
Sea Urchin Strong. purpuratus XP_785865 586 60667 V234 K T I S T T S V P S L V T T Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.9 34.2 46 N.A. 95.3 96.3 N.A. 31.9 33.6 28.6 39.5 N.A. 24.8 29.8 30 33.9
Protein Similarity: 100 51.9 48.1 46.3 N.A. 96.6 97 N.A. 37.6 47.6 40.8 43.9 N.A. 37.7 37.4 42.6 42.1
P-Site Identity: 100 100 0 93.3 N.A. 93.3 100 N.A. 0 20 6.6 33.3 N.A. 26.6 6.6 6.6 26.6
P-Site Similarity: 100 100 0 93.3 N.A. 100 100 N.A. 26.6 26.6 33.3 40 N.A. 40 33.3 13.3 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 0 8 0 8 8 50 8 15 8 0 22 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 8 0 0 0 0 0 8 % D
% Glu: 0 0 0 0 0 0 36 0 0 0 0 0 43 8 0 % E
% Phe: 0 15 0 8 0 0 8 0 0 0 8 0 0 0 8 % F
% Gly: 0 8 0 0 0 0 0 0 0 0 8 0 8 8 8 % G
% His: 15 0 8 8 0 8 15 0 0 8 0 0 8 15 8 % H
% Ile: 0 8 15 8 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 36 0 0 0 8 0 0 8 8 43 0 0 0 0 % K
% Leu: 0 8 0 15 8 8 0 22 8 0 8 8 0 15 0 % L
% Met: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 15 0 8 8 0 0 0 8 8 0 0 0 % N
% Pro: 0 8 36 0 8 43 8 8 58 15 0 15 0 0 8 % P
% Gln: 29 0 15 0 0 8 8 0 0 0 0 8 8 0 43 % Q
% Arg: 36 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 8 8 43 8 8 15 36 0 15 8 43 15 0 0 % S
% Thr: 8 15 0 8 65 8 0 8 0 8 8 0 15 8 0 % T
% Val: 0 0 8 0 0 0 0 15 0 0 0 8 0 50 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 8 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _