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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POU6F1 All Species: 22.73
Human Site: T124 Identified Species: 38.46
UniProt: Q14863 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14863 NP_002693.3 301 32645 T124 I T C S E T P T V S Q L V S K
Chimpanzee Pan troglodytes XP_001149146 579 59816 T402 I T C S E T P T V S Q L V S K
Rhesus Macaque Macaca mulatta Q28503 291 32940 E128 P I D M D S P E I R E L E K F
Dog Lupus familis XP_543666 643 66150 T466 I T C S E T P T V S Q L V S K
Cat Felis silvestris
Mouse Mus musculus Q07916 301 32833 T124 I T C S E T P T V S Q L V S K
Rat Rattus norvegicus P56223 301 32683 T124 I T C S E T P T V S Q L V S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512107 672 71126 S434 Q A S S S S S S S S S S S A L
Chicken Gallus gallus Q9YGL7 363 40431 S188 E F R R K S K S V E E P V D M
Frog Xenopus laevis Q91989 426 47235 P129 F A Q Y W H Y P S W Q Q G N L
Zebra Danio Brachydanio rerio P31367 610 63106 G425 V T S L T A A G V I A C G E M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P16241 427 45909 A147 A P H A G H Y A P T G G S P L
Honey Bee Apis mellifera XP_391982 671 72301 Q376 L L S A M Q P Q Q L L Q A A Q
Nematode Worm Caenorhab. elegans P20268 380 42556 S136 S V V T S T P S C Q I K Q E V
Sea Urchin Strong. purpuratus XP_785865 586 60667 P280 Q S V H I S H P S T T S N P T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.9 34.2 46 N.A. 95.3 96.3 N.A. 31.9 33.6 28.6 39.5 N.A. 24.8 29.8 30 33.9
Protein Similarity: 100 51.9 48.1 46.3 N.A. 96.6 97 N.A. 37.6 47.6 40.8 43.9 N.A. 37.7 37.4 42.6 42.1
P-Site Identity: 100 100 13.3 100 N.A. 100 100 N.A. 13.3 13.3 6.6 13.3 N.A. 0 6.6 13.3 0
P-Site Similarity: 100 100 40 100 N.A. 100 100 N.A. 33.3 40 13.3 20 N.A. 13.3 33.3 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 15 0 15 0 8 8 8 0 0 8 0 8 15 0 % A
% Cys: 0 0 36 0 0 0 0 0 8 0 0 8 0 0 0 % C
% Asp: 0 0 8 0 8 0 0 0 0 0 0 0 0 8 0 % D
% Glu: 8 0 0 0 36 0 0 8 0 8 15 0 8 15 0 % E
% Phe: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 0 0 0 0 8 0 0 8 0 0 8 8 15 0 0 % G
% His: 0 0 8 8 0 15 8 0 0 0 0 0 0 0 0 % H
% Ile: 36 8 0 0 8 0 0 0 8 8 8 0 0 0 0 % I
% Lys: 0 0 0 0 8 0 8 0 0 0 0 8 0 8 36 % K
% Leu: 8 8 0 8 0 0 0 0 0 8 8 43 0 0 22 % L
% Met: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 15 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % N
% Pro: 8 8 0 0 0 0 58 15 8 0 0 8 0 15 0 % P
% Gln: 15 0 8 0 0 8 0 8 8 8 43 15 8 0 8 % Q
% Arg: 0 0 8 8 0 0 0 0 0 8 0 0 0 0 0 % R
% Ser: 8 8 22 43 15 29 8 22 22 43 8 15 15 36 0 % S
% Thr: 0 43 0 8 8 43 0 36 0 15 8 0 0 0 8 % T
% Val: 8 8 15 0 0 0 0 0 50 0 0 0 43 0 8 % V
% Trp: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 15 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _