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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POU6F1 All Species: 21.82
Human Site: Y252 Identified Species: 36.92
UniProt: Q14863 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14863 NP_002693.3 301 32645 Y252 A I E A L N A Y F E K N P L P
Chimpanzee Pan troglodytes XP_001149146 579 59816 Y530 A I E A L N A Y F E K N P L P
Rhesus Macaque Macaca mulatta Q28503 291 32940 H232 A K D A L E R H F G E Q N K P
Dog Lupus familis XP_543666 643 66150 Y594 A I E A L N A Y F E K N P L P
Cat Felis silvestris
Mouse Mus musculus Q07916 301 32833 Y252 A I E A L N A Y F E K N P L P
Rat Rattus norvegicus P56223 301 32683 Y252 A I E A L N A Y F E K N P L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512107 672 71126 H606 A L E I L N A H F E K N T H P
Chicken Gallus gallus Q9YGL7 363 40431 H303 A K E A L E R H F G E Q S K P
Frog Xenopus laevis Q91989 426 47235 H314 L K G Q L E G H F M C N Q K P
Zebra Danio Brachydanio rerio P31367 610 63106 Y561 A I E V L N T Y F E K N S L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P16241 427 45909 H322 V K G A L E Q H F H K Q P K P
Honey Bee Apis mellifera XP_391982 671 72301 H622 A L E L L N A H F D R N T H P
Nematode Worm Caenorhab. elegans P20268 380 42556 H299 V K S R L E F H F Q S N Q K P
Sea Urchin Strong. purpuratus XP_785865 586 60667 H514 A L E Y L S R H F E K N T H P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.9 34.2 46 N.A. 95.3 96.3 N.A. 31.9 33.6 28.6 39.5 N.A. 24.8 29.8 30 33.9
Protein Similarity: 100 51.9 48.1 46.3 N.A. 96.6 97 N.A. 37.6 47.6 40.8 43.9 N.A. 37.7 37.4 42.6 42.1
P-Site Identity: 100 100 33.3 100 N.A. 100 100 N.A. 66.6 40 26.6 80 N.A. 40 53.3 26.6 53.3
P-Site Similarity: 100 100 53.3 100 N.A. 100 100 N.A. 80 53.3 33.3 80 N.A. 46.6 80 40 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 79 0 0 58 0 0 50 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 0 8 0 0 0 0 0 % D
% Glu: 0 0 72 0 0 36 0 0 0 58 15 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 8 0 100 0 0 0 0 0 0 % F
% Gly: 0 0 15 0 0 0 8 0 0 15 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 58 0 8 0 0 0 22 0 % H
% Ile: 0 43 0 8 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 36 0 0 0 0 0 0 0 0 65 0 0 36 0 % K
% Leu: 8 22 0 8 100 0 0 0 0 0 0 0 0 43 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 58 0 0 0 0 0 79 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 43 0 100 % P
% Gln: 0 0 0 8 0 0 8 0 0 8 0 22 15 0 0 % Q
% Arg: 0 0 0 8 0 0 22 0 0 0 8 0 0 0 0 % R
% Ser: 0 0 8 0 0 8 0 0 0 0 8 0 15 0 0 % S
% Thr: 0 0 0 0 0 0 8 0 0 0 0 0 22 0 0 % T
% Val: 15 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 43 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _