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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POU6F1
All Species:
35.15
Human Site:
Y273
Identified Species:
59.49
UniProt:
Q14863
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14863
NP_002693.3
301
32645
Y273
E
I
A
K
E
L
N
Y
D
R
E
V
V
R
V
Chimpanzee
Pan troglodytes
XP_001149146
579
59816
Y551
E
I
A
K
E
L
N
Y
D
R
E
V
V
R
V
Rhesus Macaque
Macaca mulatta
Q28503
291
32940
L253
R
M
A
E
E
L
N
L
E
K
E
V
V
R
V
Dog
Lupus familis
XP_543666
643
66150
Y615
E
I
A
K
E
L
N
Y
D
R
E
V
V
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q07916
301
32833
Y273
E
I
A
K
E
L
N
Y
D
R
E
V
V
R
V
Rat
Rattus norvegicus
P56223
301
32683
Y273
E
I
A
K
E
L
N
Y
D
R
E
V
V
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512107
672
71126
Y627
E
I
A
E
K
L
N
Y
D
R
E
V
V
R
V
Chicken
Gallus gallus
Q9YGL7
363
40431
L324
R
M
A
E
G
L
N
L
E
K
E
V
V
R
V
Frog
Xenopus laevis
Q91989
426
47235
L335
E
I
A
K
E
L
S
L
E
K
D
V
V
R
V
Zebra Danio
Brachydanio rerio
P31367
610
63106
Y582
E
I
A
K
E
L
N
Y
D
R
E
V
V
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16241
427
45909
L343
S
L
A
D
S
L
Q
L
E
K
E
V
V
R
V
Honey Bee
Apis mellifera
XP_391982
671
72301
Y643
N
L
A
Q
R
L
G
Y
D
R
E
V
I
R
I
Nematode Worm
Caenorhab. elegans
P20268
380
42556
L320
Q
V
A
M
E
L
Q
L
E
K
E
V
V
R
V
Sea Urchin
Strong. purpuratus
XP_785865
586
60667
Y535
A
L
A
Q
E
L
N
Y
D
R
E
V
I
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.9
34.2
46
N.A.
95.3
96.3
N.A.
31.9
33.6
28.6
39.5
N.A.
24.8
29.8
30
33.9
Protein Similarity:
100
51.9
48.1
46.3
N.A.
96.6
97
N.A.
37.6
47.6
40.8
43.9
N.A.
37.7
37.4
42.6
42.1
P-Site Identity:
100
100
60
100
N.A.
100
100
N.A.
86.6
53.3
66.6
100
N.A.
46.6
53.3
53.3
73.3
P-Site Similarity:
100
100
86.6
100
N.A.
100
100
N.A.
100
80
93.3
100
N.A.
66.6
80
80
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
65
0
8
0
0
0
0
% D
% Glu:
58
0
0
22
72
0
0
0
36
0
93
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
58
0
0
0
0
0
0
0
0
0
0
15
0
8
% I
% Lys:
0
0
0
50
8
0
0
0
0
36
0
0
0
0
0
% K
% Leu:
0
22
0
0
0
100
0
36
0
0
0
0
0
0
0
% L
% Met:
0
15
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
72
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
15
0
0
15
0
0
0
0
0
0
0
0
% Q
% Arg:
15
0
0
0
8
0
0
0
0
65
0
0
0
100
0
% R
% Ser:
8
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
100
86
0
93
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _