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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYBPC3
All Species:
16.67
Human Site:
T274
Identified Species:
40.74
UniProt:
Q14896
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14896
NP_000247.2
1273
140606
T274
L
L
S
A
F
R
R
T
S
L
A
G
G
G
R
Chimpanzee
Pan troglodytes
XP_508410
1219
134426
T274
L
L
S
A
F
R
R
T
D
S
K
L
E
A
P
Rhesus Macaque
Macaca mulatta
XP_001091952
1171
131678
I256
K
I
A
F
Q
Y
G
I
T
D
L
R
G
M
L
Dog
Lupus familis
XP_533608
1141
128021
K246
R
G
M
L
K
R
L
K
K
A
K
V
E
V
K
Cat
Felis silvestris
Mouse
Mus musculus
O70468
1270
140614
T272
L
R
S
A
F
R
R
T
S
L
A
G
A
G
R
Rat
Rattus norvegicus
Q63518
621
68718
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506731
1227
137283
R282
D
I
R
S
A
F
K
R
S
G
E
G
Q
E
D
Chicken
Gallus gallus
Q90688
1272
142270
T264
I
R
A
A
F
R
R
T
S
L
A
G
G
G
R
Frog
Xenopus laevis
NP_001082167
1282
144058
T279
I
R
A
A
F
R
R
T
S
L
V
G
A
A
K
Zebra Danio
Brachydanio rerio
NP_001037814
1265
142292
T290
I
R
T
A
F
R
R
T
S
T
D
A
G
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.9
46.8
51.1
N.A.
88.4
20.5
N.A.
45.9
69.4
64.7
63.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
94.4
63.9
65
N.A.
91.9
32.4
N.A.
62.4
82.3
78.7
76.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
6.6
6.6
N.A.
86.6
0
N.A.
13.3
80
53.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
53.3
26.6
13.3
N.A.
86.6
0
N.A.
33.3
93.3
73.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
30
60
10
0
0
0
0
10
30
10
20
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
10
10
10
0
0
10
20
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
0
20
10
0
% E
% Phe:
0
0
0
10
60
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
10
0
0
10
0
50
40
30
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
30
20
0
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
10
0
10
10
10
0
20
0
0
0
20
% K
% Leu:
30
20
0
10
0
0
10
0
0
40
10
10
0
0
10
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
10
40
10
0
0
70
60
10
0
0
0
10
0
0
30
% R
% Ser:
0
0
30
10
0
0
0
0
60
10
0
0
0
0
0
% S
% Thr:
0
0
10
0
0
0
0
60
10
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _