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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYBPC3 All Species: 2.12
Human Site: T290 Identified Species: 5.19
UniProt: Q14896 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14896 NP_000247.2 1273 140606 T290 I S D S H E D T G I L D F S S
Chimpanzee Pan troglodytes XP_508410 1219 134426 L290 E E D V W E I L R Q A P P S E
Rhesus Macaque Macaca mulatta XP_001091952 1171 131678 V272 R L K R M R R V E K K S A A F
Dog Lupus familis XP_533608 1141 128021 L262 S A A F T K K L D P A Y Q V D
Cat Felis silvestris
Mouse Mus musculus O70468 1270 140614 A288 T S D S H E D A G T P D F S S
Rat Rattus norvegicus Q63518 621 68718
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506731 1227 137283 L298 G E L D F S G L L K R R E I K
Chicken Gallus gallus Q90688 1272 142270 T280 M T S A F L S T E G L E E S G
Frog Xenopus laevis NP_001082167 1282 144058 G295 R V S I A F S G D G T E E A G
Zebra Danio Brachydanio rerio NP_001037814 1265 142292 L306 G E L D F S A L L K K R D S F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.9 46.8 51.1 N.A. 88.4 20.5 N.A. 45.9 69.4 64.7 63.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 94.4 63.9 65 N.A. 91.9 32.4 N.A. 62.4 82.3 78.7 76.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 20 0 0 N.A. 73.3 0 N.A. 0 20 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 6.6 13.3 N.A. 73.3 0 N.A. 0 46.6 13.3 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 10 10 0 10 10 0 0 20 0 10 20 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 30 20 0 0 20 0 20 0 0 20 10 0 10 % D
% Glu: 10 30 0 0 0 30 0 0 20 0 0 20 30 0 10 % E
% Phe: 0 0 0 10 30 10 0 0 0 0 0 0 20 0 20 % F
% Gly: 20 0 0 0 0 0 10 10 20 20 0 0 0 0 20 % G
% His: 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 10 0 0 10 0 0 10 0 0 0 10 0 % I
% Lys: 0 0 10 0 0 10 10 0 0 30 20 0 0 0 10 % K
% Leu: 0 10 20 0 0 10 0 40 20 0 20 0 0 0 0 % L
% Met: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 10 10 10 10 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 10 0 0 % Q
% Arg: 20 0 0 10 0 10 10 0 10 0 10 20 0 0 0 % R
% Ser: 10 20 20 20 0 20 20 0 0 0 0 10 0 50 20 % S
% Thr: 10 10 0 0 10 0 0 20 0 10 10 0 0 0 0 % T
% Val: 0 10 0 10 0 0 0 10 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _