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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC17A1 All Species: 23.94
Human Site: S248 Identified Species: 47.88
UniProt: Q14916 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14916 NP_005065.2 467 51132 S248 S L V Q Q V S S S R Q S L P I
Chimpanzee Pan troglodytes XP_518283 517 56759 S298 S L V Q Q V S S S R Q S L P I
Rhesus Macaque Macaca mulatta XP_001083774 498 54349 S280 S L K Q Q V R S S Q Q P L P I
Dog Lupus familis XP_545377 526 57357 S307 S L A Q Q S S S P R R S V P I
Cat Felis silvestris
Mouse Mus musculus Q61983 465 51571 S246 S L M Q Q A S S G R Q S L P I
Rat Rattus norvegicus Q62795 465 51332 S246 S L M Q Q V H S G R Q S L P I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519993 502 53998 S280 S L T H Q S N S Q G R S L P I
Chicken Gallus gallus
Frog Xenopus laevis Q6INC8 576 63887 M288 S T G F M N P M A K F K A P W
Zebra Danio Brachydanio rerio Q1L8X9 590 64796 T301 G A N L M S S T E K F K T P W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V7S5 529 58354 V280 S L W G T D V V K S P P I P F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34644 576 63090 P291 G H V S N T H P T I R S I P W
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GX78 541 59595 E323 D D P D L S E E E K K V I L G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.9 46.1 46.5 N.A. 65.3 64.8 N.A. 39.4 N.A. 25.8 26.7 N.A. 26.6 N.A. 26.5 N.A.
Protein Similarity: 100 89.7 62.8 63.1 N.A. 78.3 77.9 N.A. 57.3 N.A. 42.3 42.3 N.A. 44 N.A. 43.2 N.A.
P-Site Identity: 100 100 73.3 66.6 N.A. 80 80 N.A. 53.3 N.A. 13.3 13.3 N.A. 20 N.A. 20 N.A.
P-Site Similarity: 100 100 80 80 N.A. 86.6 86.6 N.A. 66.6 N.A. 26.6 26.6 N.A. 26.6 N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 0 0 9 0 0 9 0 0 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 9 0 9 0 9 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 9 9 17 0 0 0 0 0 0 % E
% Phe: 0 0 0 9 0 0 0 0 0 0 17 0 0 0 9 % F
% Gly: 17 0 9 9 0 0 0 0 17 9 0 0 0 0 9 % G
% His: 0 9 0 9 0 0 17 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 0 0 25 0 59 % I
% Lys: 0 0 9 0 0 0 0 0 9 25 9 17 0 0 0 % K
% Leu: 0 67 0 9 9 0 0 0 0 0 0 0 50 9 0 % L
% Met: 0 0 17 0 17 0 0 9 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 9 9 9 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 9 0 0 0 9 9 9 0 9 17 0 92 0 % P
% Gln: 0 0 0 50 59 0 0 0 9 9 42 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 9 0 0 42 25 0 0 0 0 % R
% Ser: 75 0 0 9 0 34 42 59 25 9 0 59 0 0 0 % S
% Thr: 0 9 9 0 9 9 0 9 9 0 0 0 9 0 0 % T
% Val: 0 0 25 0 0 34 9 9 0 0 0 9 9 0 0 % V
% Trp: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 25 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _