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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NFATC4
All Species:
31.82
Human Site:
T435
Identified Species:
100
UniProt:
Q14934
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14934
NP_001129494.1
902
95449
T435
H
H
R
A
H
Y
E
T
E
G
S
R
G
A
V
Chimpanzee
Pan troglodytes
XP_001170077
901
95367
T435
H
H
R
A
H
Y
E
T
E
G
S
R
G
A
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537395
901
95556
T435
H
H
R
A
H
Y
E
T
E
G
S
R
G
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8K120
901
95763
T435
H
H
R
A
H
Y
E
T
E
G
S
R
G
A
V
Rat
Rattus norvegicus
NP_001100734
901
95745
T435
H
H
R
A
H
Y
E
T
E
G
S
R
G
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414078
1211
130585
T571
H
H
R
A
H
Y
E
T
E
G
S
R
G
A
V
Frog
Xenopus laevis
NP_001082217
884
97675
T425
H
H
R
A
H
Y
E
T
E
G
S
R
G
A
V
Zebra Danio
Brachydanio rerio
XP_690273
1074
115220
T459
H
H
R
A
H
Y
E
T
E
G
S
R
G
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
N.A.
94.9
N.A.
92.5
92.7
N.A.
N.A.
36.5
39.5
40.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
N.A.
96
N.A.
94.5
94.6
N.A.
N.A.
47.1
53.2
52.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
100
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
100
0
0
0
0
0
0
0
0
0
100
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
100
0
100
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
100
0
0
100
0
0
% G
% His:
100
100
0
0
100
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
100
0
0
0
0
0
0
0
0
100
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
88
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _