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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRIN2C All Species: 17.58
Human Site: S391 Identified Species: 38.67
UniProt: Q14957 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14957 NP_000826.2 1236 134532 S391 Y P V W P R Y S A S L Q P V V
Chimpanzee Pan troglodytes Q5IS45 1464 165261 K394 H A V W P R Y K S F S D C E P
Rhesus Macaque Macaca mulatta XP_001088140 1484 166333 M394 K Y Y V W P R M C P E T E E Q
Dog Lupus familis XP_540421 1081 117358 L325 D G V A I L A L G A H G Y Q R
Cat Felis silvestris
Mouse Mus musculus Q01098 1239 135402 S391 Y P V W P R Y S T S L Q P V V
Rat Rattus norvegicus Q00961 1237 135253 S391 Y P V W P R Y S T S L Q P V V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506052 1465 164998 S392 H S V W P R F S S F V D S D P
Chicken Gallus gallus XP_425252 1458 165503 S391 Y S V W P R Y S S F A D S D P
Frog Xenopus laevis NP_001106367 1451 164575 T386 Y P V W P R I T A S L D S D H
Zebra Danio Brachydanio rerio XP_002664030 1328 148565 G398 Y P V W P R Y G S F L E P V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24418 997 112270 Y241 Q S R V Y L M Y A S T E D A Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 41.8 40.5 78.3 N.A. 89.1 88.7 N.A. 40.8 41 41.6 54.9 N.A. 23.1 N.A. N.A. N.A.
Protein Similarity: 100 54.6 54.7 80.6 N.A. 91.9 91.5 N.A. 54.6 54.7 54.8 67.1 N.A. 40 N.A. N.A. N.A.
P-Site Identity: 100 33.3 0 6.6 N.A. 93.3 93.3 N.A. 33.3 46.6 60 66.6 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 46.6 0 13.3 N.A. 93.3 93.3 N.A. 60 53.3 66.6 80 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 0 0 10 0 28 10 10 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 37 10 28 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 10 19 10 19 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 37 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 0 10 10 0 0 10 0 0 0 % G
% His: 19 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % H
% Ile: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 19 0 10 0 0 46 0 0 0 0 % L
% Met: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 46 0 0 73 10 0 0 0 10 0 0 37 0 28 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 0 28 0 10 19 % Q
% Arg: 0 0 10 0 0 73 10 0 0 0 0 0 0 0 10 % R
% Ser: 0 28 0 0 0 0 0 46 37 46 10 0 28 0 10 % S
% Thr: 0 0 0 0 0 0 0 10 19 0 10 10 0 0 0 % T
% Val: 0 0 82 19 0 0 0 0 0 0 10 0 0 37 28 % V
% Trp: 0 0 0 73 10 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 55 10 10 0 10 0 55 10 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _