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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRIN2C
All Species:
16.97
Human Site:
S418
Identified Species:
37.33
UniProt:
Q14957
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14957
NP_000826.2
1236
134532
S418
R
P
F
V
I
V
E
S
P
D
P
G
T
G
G
Chimpanzee
Pan troglodytes
Q5IS45
1464
165261
D421
A
P
F
V
I
V
E
D
I
D
P
L
T
E
T
Rhesus Macaque
Macaca mulatta
XP_001088140
1484
166333
S421
A
P
F
V
I
V
E
S
V
D
P
L
S
G
T
Dog
Lupus familis
XP_540421
1081
117358
S352
R
G
H
P
G
P
V
S
P
A
R
E
A
F
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q01098
1239
135402
S418
R
P
F
V
I
V
E
S
P
D
P
G
T
G
G
Rat
Rattus norvegicus
Q00961
1237
135253
S418
R
P
F
V
I
V
E
S
P
D
P
G
T
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506052
1465
164998
D419
A
P
F
V
I
V
E
D
M
D
P
L
T
E
T
Chicken
Gallus gallus
XP_425252
1458
165503
D418
A
P
F
V
I
V
E
D
V
D
P
L
M
E
S
Frog
Xenopus laevis
NP_001106367
1451
164575
N413
A
P
F
V
I
V
E
N
I
D
Y
L
T
G
T
Zebra Danio
Brachydanio rerio
XP_002664030
1328
148565
S425
R
P
F
V
I
V
E
S
V
D
P
A
T
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24418
997
112270
V268
G
E
G
H
V
W
I
V
T
E
Q
A
L
F
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.8
40.5
78.3
N.A.
89.1
88.7
N.A.
40.8
41
41.6
54.9
N.A.
23.1
N.A.
N.A.
N.A.
Protein Similarity:
100
54.6
54.7
80.6
N.A.
91.9
91.5
N.A.
54.6
54.7
54.8
67.1
N.A.
40
N.A.
N.A.
N.A.
P-Site Identity:
100
60
66.6
20
N.A.
100
100
N.A.
60
53.3
60
80
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
60
73.3
20
N.A.
100
100
N.A.
60
53.3
66.6
80
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
46
0
0
0
0
0
0
0
0
10
0
19
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
28
0
82
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
82
0
0
10
0
10
0
28
0
% E
% Phe:
0
0
82
0
0
0
0
0
0
0
0
0
0
19
0
% F
% Gly:
10
10
10
0
10
0
0
0
0
0
0
28
0
55
28
% G
% His:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
82
0
10
0
19
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
46
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
82
0
10
0
10
0
0
37
0
73
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
46
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
55
0
0
0
0
10
0
19
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
0
0
64
0
46
% T
% Val:
0
0
0
82
10
82
10
10
28
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _