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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRIN2C All Species: 16.97
Human Site: S418 Identified Species: 37.33
UniProt: Q14957 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14957 NP_000826.2 1236 134532 S418 R P F V I V E S P D P G T G G
Chimpanzee Pan troglodytes Q5IS45 1464 165261 D421 A P F V I V E D I D P L T E T
Rhesus Macaque Macaca mulatta XP_001088140 1484 166333 S421 A P F V I V E S V D P L S G T
Dog Lupus familis XP_540421 1081 117358 S352 R G H P G P V S P A R E A F Y
Cat Felis silvestris
Mouse Mus musculus Q01098 1239 135402 S418 R P F V I V E S P D P G T G G
Rat Rattus norvegicus Q00961 1237 135253 S418 R P F V I V E S P D P G T G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506052 1465 164998 D419 A P F V I V E D M D P L T E T
Chicken Gallus gallus XP_425252 1458 165503 D418 A P F V I V E D V D P L M E S
Frog Xenopus laevis NP_001106367 1451 164575 N413 A P F V I V E N I D Y L T G T
Zebra Danio Brachydanio rerio XP_002664030 1328 148565 S425 R P F V I V E S V D P A T G T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24418 997 112270 V268 G E G H V W I V T E Q A L F S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 41.8 40.5 78.3 N.A. 89.1 88.7 N.A. 40.8 41 41.6 54.9 N.A. 23.1 N.A. N.A. N.A.
Protein Similarity: 100 54.6 54.7 80.6 N.A. 91.9 91.5 N.A. 54.6 54.7 54.8 67.1 N.A. 40 N.A. N.A. N.A.
P-Site Identity: 100 60 66.6 20 N.A. 100 100 N.A. 60 53.3 60 80 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 60 73.3 20 N.A. 100 100 N.A. 60 53.3 66.6 80 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 46 0 0 0 0 0 0 0 0 10 0 19 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 28 0 82 0 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 82 0 0 10 0 10 0 28 0 % E
% Phe: 0 0 82 0 0 0 0 0 0 0 0 0 0 19 0 % F
% Gly: 10 10 10 0 10 0 0 0 0 0 0 28 0 55 28 % G
% His: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 82 0 10 0 19 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 46 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 82 0 10 0 10 0 0 37 0 73 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Q
% Arg: 46 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 55 0 0 0 0 10 0 19 % S
% Thr: 0 0 0 0 0 0 0 0 10 0 0 0 64 0 46 % T
% Val: 0 0 0 82 10 82 10 10 28 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _