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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC10A1
All Species:
20.91
Human Site:
Y183
Identified Species:
51.11
UniProt:
Q14973
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14973
NP_003040.1
349
38119
Y183
L
K
S
K
R
P
Q
Y
M
R
Y
V
I
K
G
Chimpanzee
Pan troglodytes
XP_510035
349
38135
Y183
L
K
S
K
R
P
Q
Y
M
R
Y
V
I
K
G
Rhesus Macaque
Macaca mulatta
XP_001110268
349
38086
Y183
L
K
S
K
R
P
Q
Y
M
R
Y
V
I
K
G
Dog
Lupus familis
XP_537494
392
42759
Y183
L
K
A
K
R
P
Q
Y
V
R
Y
I
K
K
G
Cat
Felis silvestris
Mouse
Mus musculus
O08705
362
39395
Y183
L
K
S
K
R
P
H
Y
V
P
Y
V
L
K
A
Rat
Rattus norvegicus
P26435
362
39277
Y183
L
K
S
K
R
P
H
Y
V
P
Y
I
L
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513365
346
37888
A189
N
S
K
W
P
E
K
A
K
I
I
L
K
I
G
Chicken
Gallus gallus
XP_425589
360
39281
A200
N
H
K
W
P
S
K
A
K
R
I
L
K
V
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690745
240
26762
F84
G
G
N
L
S
N
I
F
A
L
A
L
Q
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794542
370
41448
K177
W
W
R
K
E
W
T
K
Y
I
T
R
V
G
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.2
76.2
N.A.
74.8
75.1
N.A.
35.2
36.1
N.A.
42.4
N.A.
N.A.
N.A.
N.A.
33.7
Protein Similarity:
100
99.4
98.5
80.6
N.A.
81.7
83.1
N.A.
57
55.2
N.A.
55
N.A.
N.A.
N.A.
N.A.
50.5
P-Site Identity:
100
100
100
73.3
N.A.
66.6
66.6
N.A.
6.6
13.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
80
86.6
N.A.
20
26.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
20
10
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
0
0
0
0
0
0
0
0
0
20
70
% G
% His:
0
10
0
0
0
0
20
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
20
20
20
30
10
10
% I
% Lys:
0
60
20
70
0
0
20
10
20
0
0
0
30
60
0
% K
% Leu:
60
0
0
10
0
0
0
0
0
10
0
30
20
0
0
% L
% Met:
0
0
0
0
0
0
0
0
30
0
0
0
0
0
0
% M
% Asn:
20
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
20
60
0
0
0
20
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
40
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
10
0
60
0
0
0
0
50
0
10
0
0
0
% R
% Ser:
0
10
50
0
10
10
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
30
0
0
40
10
10
0
% V
% Trp:
10
10
0
20
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
10
0
60
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _