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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KPNB1 All Species: 25.76
Human Site: S108 Identified Species: 51.52
UniProt: Q14974 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14974 NP_002256.2 876 97170 S108 T E T Y R P S S A S Q C V A G
Chimpanzee Pan troglodytes XP_511927 918 101671 S150 T E T Y R P S S A S Q C V A G
Rhesus Macaque Macaca mulatta XP_001082833 1044 114674 S276 T E T Y R P S S A S Q C V A G
Dog Lupus familis XP_548162 876 97209 S108 T E T Y R P S S A S Q C V A G
Cat Felis silvestris
Mouse Mus musculus P70168 876 97134 S108 T E T Y R P S S A S Q C V A G
Rat Rattus norvegicus P52296 875 97106 S107 T E T Y R P S S A S Q C V A G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis P52297 260 28799
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O18388 884 98677 C114 T E N T R P S C A A Q C V A Y
Honey Bee Apis mellifera XP_393927 894 99270 S115 T E N N R P G S A P Q C V A Y
Nematode Worm Caenorhab. elegans NP_491477 896 98740 I114 T E P S R P S I A A Q C V A A
Sea Urchin Strong. purpuratus XP_781574 862 96235 E100 I A G I A C T E L P A E L W P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06142 861 94757 N113 S I E P R I A N A A A Q L I A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.5 82.6 99.4 N.A. 99 98.5 N.A. N.A. N.A. 23.8 N.A. N.A. 61 66.8 48.2 67.2
Protein Similarity: 100 93.7 83.6 99.6 N.A. 99.7 99.1 N.A. N.A. N.A. 25.6 N.A. N.A. 76.4 79.4 65.9 80.5
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 0 N.A. N.A. 66.6 66.6 66.6 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 0 N.A. N.A. 73.3 66.6 73.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 34.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 55 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 9 0 9 0 84 25 17 0 0 75 17 % A
% Cys: 0 0 0 0 0 9 0 9 0 0 0 75 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 75 9 0 0 0 0 9 0 0 0 9 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 0 0 9 0 0 0 0 0 0 0 50 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 9 0 9 0 9 0 9 0 0 0 0 0 9 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 9 0 0 0 17 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 17 9 0 0 0 9 0 0 0 0 0 0 0 % N
% Pro: 0 0 9 9 0 75 0 0 0 17 0 0 0 0 9 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 75 9 0 0 0 % Q
% Arg: 0 0 0 0 84 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 9 0 0 9 0 0 67 59 0 50 0 0 0 0 0 % S
% Thr: 75 0 50 9 0 0 9 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 75 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % W
% Tyr: 0 0 0 50 0 0 0 0 0 0 0 0 0 0 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _