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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KPNB1 All Species: 25.15
Human Site: T855 Identified Species: 50.3
UniProt: Q14974 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14974 NP_002256.2 876 97170 T855 T E G R R S K T N K A K T L A
Chimpanzee Pan troglodytes XP_511927 918 101671 T897 T E G R R S K T N K A K T L A
Rhesus Macaque Macaca mulatta XP_001082833 1044 114674 T1023 T E G R R S K T N K A K T L A
Dog Lupus familis XP_548162 876 97209 T855 T E G R R S K T N K A K T L A
Cat Felis silvestris
Mouse Mus musculus P70168 876 97134 T855 T E G R R S K T N K A K T L A
Rat Rattus norvegicus P52296 875 97106 T854 T E G R R S K T N K A K T L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis P52297 260 28799 H242 K L V E A R I H E L L T E G K
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O18388 884 98677 A860 A E G K R S K A Q R T K M L C
Honey Bee Apis mellifera XP_393927 894 99270 I863 T K A R R S R I D K T K T L A
Nematode Worm Caenorhab. elegans NP_491477 896 98740 V867 Q K G R K S K V S K T K S M A
Sea Urchin Strong. purpuratus XP_781574 862 96235 V836 T E G R R S K V M K T K T L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06142 861 94757 S836 D Y I K R T R S G Q L F S Q A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.5 82.6 99.4 N.A. 99 98.5 N.A. N.A. N.A. 23.8 N.A. N.A. 61 66.8 48.2 67.2
Protein Similarity: 100 93.7 83.6 99.6 N.A. 99.7 99.1 N.A. N.A. N.A. 25.6 N.A. N.A. 76.4 79.4 65.9 80.5
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 0 N.A. N.A. 46.6 60 46.6 80
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 0 N.A. N.A. 60 80 80 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 34.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 55 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 0 9 0 0 9 0 0 50 0 0 0 84 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % D
% Glu: 0 67 0 9 0 0 0 0 9 0 0 0 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % F
% Gly: 0 0 75 0 0 0 0 0 9 0 0 0 0 9 0 % G
% His: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 0 0 0 9 9 0 0 0 0 0 0 0 % I
% Lys: 9 17 0 17 9 0 75 0 0 75 0 84 0 0 9 % K
% Leu: 0 9 0 0 0 0 0 0 0 9 17 0 0 75 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 9 9 0 % M
% Asn: 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 9 0 0 0 0 0 0 0 9 9 0 0 0 9 0 % Q
% Arg: 0 0 0 75 84 9 17 0 0 9 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 84 0 9 9 0 0 0 17 0 0 % S
% Thr: 67 0 0 0 0 9 0 50 0 0 34 9 67 0 0 % T
% Val: 0 0 9 0 0 0 0 17 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _