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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KPNB1 All Species: 17.88
Human Site: Y752 Identified Species: 35.76
UniProt: Q14974 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14974 NP_002256.2 876 97170 Y752 A Q V D K S D Y D M V D Y L N
Chimpanzee Pan troglodytes XP_511927 918 101671 Y794 A Q V D K S D Y D M V D Y L N
Rhesus Macaque Macaca mulatta XP_001082833 1044 114674 Y920 A Q V D K S D Y D M V D Y L N
Dog Lupus familis XP_548162 876 97209 Y752 A Q V D K S D Y D M V D Y L N
Cat Felis silvestris
Mouse Mus musculus P70168 876 97134 F752 A Q V D K S D F D M V D Y L N
Rat Rattus norvegicus P52296 875 97106 F751 A Q V D K S D F D M V D Y L N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis P52297 260 28799 Q160 T D R P D G H Q N N L D V V M
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O18388 884 98677 F758 L Q T D A N N F D M N E Y I N
Honey Bee Apis mellifera XP_393927 894 99270 Y759 A N V D R S D Y D M I D Y L N
Nematode Worm Caenorhab. elegans NP_491477 896 98740 D764 V V T D P N D D D Q V D Y V D
Sea Urchin Strong. purpuratus XP_781574 862 96235 F734 A E I E K T D F D M I D Y L N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06142 861 94757 L741 T K P E N G T L E A L D Y Q I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.5 82.6 99.4 N.A. 99 98.5 N.A. N.A. N.A. 23.8 N.A. N.A. 61 66.8 48.2 67.2
Protein Similarity: 100 93.7 83.6 99.6 N.A. 99.7 99.1 N.A. N.A. N.A. 25.6 N.A. N.A. 76.4 79.4 65.9 80.5
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. N.A. 6.6 N.A. N.A. 40 80 40 60
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 26.6 N.A. N.A. 73.3 93.3 60 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. 34.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 55 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 67 0 0 0 9 0 0 0 0 9 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 75 9 0 75 9 84 0 0 92 0 0 9 % D
% Glu: 0 9 0 17 0 0 0 0 9 0 0 9 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 34 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 0 0 0 0 0 0 0 17 0 0 9 9 % I
% Lys: 0 9 0 0 59 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 0 0 0 0 0 0 9 0 0 17 0 0 67 0 % L
% Met: 0 0 0 0 0 0 0 0 0 75 0 0 0 0 9 % M
% Asn: 0 9 0 0 9 17 9 0 9 9 9 0 0 0 75 % N
% Pro: 0 0 9 9 9 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 59 0 0 0 0 0 9 0 9 0 0 0 9 0 % Q
% Arg: 0 0 9 0 9 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 59 0 0 0 0 0 0 0 0 0 % S
% Thr: 17 0 17 0 0 9 9 0 0 0 0 0 0 0 0 % T
% Val: 9 9 59 0 0 0 0 0 0 0 59 0 9 17 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 42 0 0 0 0 92 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _