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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOLC1 All Species: 12.73
Human Site: S580 Identified Species: 21.54
UniProt: Q14978 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14978 NP_004732.2 699 73603 S580 A A V V V S K S G S L K K R K
Chimpanzee Pan troglodytes XP_001171017 700 73581 S581 A A V V V S K S G S L K K R K
Rhesus Macaque Macaca mulatta XP_001112196 701 73703 S582 A A V A V S K S G S L K K R K
Dog Lupus familis XP_851848 704 74723 P585 A V V A V S K P G S G K K R K
Cat Felis silvestris
Mouse Mus musculus O08784 1320 134983 V1155 W P L S E A Q V Q A S V V K V
Rat Rattus norvegicus P41777 704 73545 P585 K K A A G T K P G S G K K R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511079 669 69188 G527 E D Q P A S K G V G P S Q K Q
Chicken Gallus gallus XP_421630 694 72200 A575 S E E E K G K A N G G L A K K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689627 1001 102013 S882 S S S S E E S S E E E E T P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_730693 686 70584 P569 G D Q D E A T P N K K Y N N F
Honey Bee Apis mellifera XP_001120943 685 75016 H567 P K A E K R K H K E I E Q E K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796224 791 84162 S672 K R R Q S S S S E S D S D E E
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001168628 517 55362 S406 E D C T A N E S L S N G F A E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32583 406 40997 A295 A T A D E S K A E E T P A S S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 94.2 81.5 N.A. 24.9 74.1 N.A. 50.7 43.6 N.A. 36.6 N.A. 27.3 22 N.A. 34.5
Protein Similarity: 100 98.8 95.5 85.6 N.A. 36.7 81.2 N.A. 60.3 57.5 N.A. 47.5 N.A. 42.3 42.9 N.A. 47.9
P-Site Identity: 100 100 93.3 73.3 N.A. 0 46.6 N.A. 13.3 13.3 N.A. 6.6 N.A. 0 13.3 N.A. 20
P-Site Similarity: 100 100 93.3 73.3 N.A. 33.3 53.3 N.A. 33.3 33.3 N.A. 26.6 N.A. 6.6 33.3 N.A. 26.6
Percent
Protein Identity: N.A. 23.6 N.A. N.A. 25.1 N.A.
Protein Similarity: N.A. 40.9 N.A. N.A. 39.4 N.A.
P-Site Identity: N.A. 13.3 N.A. N.A. 20 N.A.
P-Site Similarity: N.A. 33.3 N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 36 22 22 22 15 15 0 15 0 8 0 0 15 8 8 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 22 0 15 0 0 0 0 0 0 8 0 8 0 0 % D
% Glu: 15 8 8 15 29 8 8 0 22 22 8 15 0 15 15 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % F
% Gly: 8 0 0 0 8 8 0 8 36 15 22 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 15 15 0 0 15 0 65 0 8 8 8 36 36 22 50 % K
% Leu: 0 0 8 0 0 0 0 0 8 0 22 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 0 15 0 8 0 8 8 0 % N
% Pro: 8 8 0 8 0 0 0 22 0 0 8 8 0 8 0 % P
% Gln: 0 0 15 8 0 0 8 0 8 0 0 0 15 0 8 % Q
% Arg: 0 8 8 0 0 8 0 0 0 0 0 0 0 36 0 % R
% Ser: 15 8 8 15 8 50 15 43 0 50 8 15 0 8 8 % S
% Thr: 0 8 0 8 0 8 8 0 0 0 8 0 8 0 0 % T
% Val: 0 8 29 15 29 0 0 8 8 0 0 8 8 0 8 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _