KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR1D2
All Species:
10.61
Human Site:
S242
Identified Species:
21.21
UniProt:
Q14995
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14995
NP_005117.3
579
64625
S242
Q
E
N
I
K
S
S
S
P
P
S
S
D
F
A
Chimpanzee
Pan troglodytes
XP_516330
579
64584
S242
Q
E
N
I
K
S
S
S
P
P
S
S
D
F
A
Rhesus Macaque
Macaca mulatta
O18924
505
57572
C180
Y
D
R
C
D
L
N
C
R
I
H
K
K
S
R
Dog
Lupus familis
XP_542763
576
64407
S240
E
Q
E
N
I
K
S
S
S
P
S
S
D
F
A
Cat
Felis silvestris
Mouse
Mus musculus
Q60674
576
64283
K239
Q
L
E
Q
E
N
I
K
N
T
P
S
D
F
A
Rat
Rattus norvegicus
Q63504
578
64173
T241
E
Q
E
N
I
K
S
T
P
P
P
S
D
F
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509051
657
72899
P319
S
P
P
P
P
P
P
P
P
P
P
S
D
F
A
Chicken
Gallus gallus
Q90966
460
50710
V135
K
N
C
I
I
N
K
V
T
R
N
R
C
Q
Y
Frog
Xenopus laevis
P37234
477
54037
L152
L
I
Y
E
R
C
D
L
N
C
R
I
H
K
K
Zebra Danio
Brachydanio rerio
NP_571140
578
63335
R227
S
S
S
P
R
S
N
R
S
E
S
S
P
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17671
1199
128515
N549
L
Q
Y
I
V
A
Q
N
R
P
D
Q
P
E
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XUK7
514
56114
V189
D
A
V
R
F
G
R
V
P
K
R
E
K
A
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
22.2
97.5
N.A.
90.8
89.4
N.A.
78.3
20.3
26.2
57.6
N.A.
20.2
N.A.
24.5
N.A.
Protein Similarity:
100
99.8
39.3
99.1
N.A.
96.1
95.1
N.A.
82.1
38.6
42.6
68.3
N.A.
33.1
N.A.
40.5
N.A.
P-Site Identity:
100
100
0
53.3
N.A.
33.3
46.6
N.A.
40
6.6
0
20
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
13.3
66.6
N.A.
46.6
66.6
N.A.
40
26.6
6.6
40
N.A.
33.3
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
9
0
0
0
0
0
0
0
9
50
% A
% Cys:
0
0
9
9
0
9
0
9
0
9
0
0
9
0
0
% C
% Asp:
9
9
0
0
9
0
9
0
0
0
9
0
50
9
0
% D
% Glu:
17
17
25
9
9
0
0
0
0
9
0
9
0
9
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
50
9
% F
% Gly:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% H
% Ile:
0
9
0
34
25
0
9
0
0
9
0
9
0
0
0
% I
% Lys:
9
0
0
0
17
17
9
9
0
9
0
9
17
9
9
% K
% Leu:
17
9
0
0
0
9
0
9
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
17
17
0
17
17
9
17
0
9
0
0
0
0
% N
% Pro:
0
9
9
17
9
9
9
9
42
50
25
0
17
0
9
% P
% Gln:
25
25
0
9
0
0
9
0
0
0
0
9
0
9
0
% Q
% Arg:
0
0
9
9
17
0
9
9
17
9
17
9
0
0
17
% R
% Ser:
17
9
9
0
0
25
34
25
17
0
34
59
0
9
0
% S
% Thr:
0
0
0
0
0
0
0
9
9
9
0
0
0
0
0
% T
% Val:
0
0
9
0
9
0
0
17
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
17
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _