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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NR1D2 All Species: 19.39
Human Site: S312 Identified Species: 38.79
UniProt: Q14995 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14995 NP_005117.3 579 64625 S312 L S S H F P C S E S Q Q H L N
Chimpanzee Pan troglodytes XP_516330 579 64584 S312 L S S H F P C S E S Q Q H L N
Rhesus Macaque Macaca mulatta O18924 505 57572 S249 L A K H L Y D S Y I K S F P L
Dog Lupus familis XP_542763 576 64407 S309 L S S H F P C S E S Q Q H L N
Cat Felis silvestris
Mouse Mus musculus Q60674 576 64283 S309 I H N H F P C S E R Q Q H L S
Rat Rattus norvegicus Q63504 578 64173 S311 L H S H F P C S E S Q Q H L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509051 657 72899 N389 L S S T H Y P N S E T E Q Q L
Chicken Gallus gallus Q90966 460 50710 Q204 E T F P A L C Q L G K Y T T N
Frog Xenopus laevis P37234 477 54037 Y221 R V L A K H L Y D S Y V K S F
Zebra Danio Brachydanio rerio NP_571140 578 63335 Q296 S H C T E K T Q E V L N H Q N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P17671 1199 128515 V620 S W A D A M D V E A A K S P L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XUK7 514 56114 V258 P I T S N F I V I P L K A A I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 22.2 97.5 N.A. 90.8 89.4 N.A. 78.3 20.3 26.2 57.6 N.A. 20.2 N.A. 24.5 N.A.
Protein Similarity: 100 99.8 39.3 99.1 N.A. 96.1 95.1 N.A. 82.1 38.6 42.6 68.3 N.A. 33.1 N.A. 40.5 N.A.
P-Site Identity: 100 100 20 100 N.A. 66.6 86.6 N.A. 20 13.3 6.6 20 N.A. 6.6 N.A. 0 N.A.
P-Site Similarity: 100 100 33.3 100 N.A. 86.6 93.3 N.A. 33.3 26.6 13.3 20 N.A. 26.6 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 9 17 0 0 0 0 9 9 0 9 9 0 % A
% Cys: 0 0 9 0 0 0 50 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 0 17 0 9 0 0 0 0 0 0 % D
% Glu: 9 0 0 0 9 0 0 0 59 9 0 9 0 0 0 % E
% Phe: 0 0 9 0 42 9 0 0 0 0 0 0 9 0 9 % F
% Gly: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % G
% His: 0 25 0 50 9 9 0 0 0 0 0 0 50 0 0 % H
% Ile: 9 9 0 0 0 0 9 0 9 9 0 0 0 0 9 % I
% Lys: 0 0 9 0 9 9 0 0 0 0 17 17 9 0 0 % K
% Leu: 50 0 9 0 9 9 9 0 9 0 17 0 0 42 25 % L
% Met: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 9 0 0 9 0 0 0 9 0 0 42 % N
% Pro: 9 0 0 9 0 42 9 0 0 9 0 0 0 17 0 % P
% Gln: 0 0 0 0 0 0 0 17 0 0 42 42 9 17 0 % Q
% Arg: 9 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % R
% Ser: 17 34 42 9 0 0 0 50 9 42 0 9 9 9 17 % S
% Thr: 0 9 9 17 0 0 9 0 0 0 9 0 9 9 0 % T
% Val: 0 9 0 0 0 0 0 17 0 9 0 9 0 0 0 % V
% Trp: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 17 0 9 9 0 9 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _