Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSME4 All Species: 19.7
Human Site: S1121 Identified Species: 43.33
UniProt: Q14997 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14997 NP_055429.2 1843 211334 S1121 S I N Q I L L S P E K I K E G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_531823 1774 204047 S1052 S S N Q T M L S S E E I K E G
Cat Felis silvestris
Mouse Mus musculus Q5SSW2 1843 211178 S1121 S I S Q T L L S P E K I K E G
Rat Rattus norvegicus NP_001020311 1843 211166 S1121 S I S Q T L L S P E K I K E G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517136 1820 208596 S1098 S I D Q E L L S P E E I K L G
Chicken Gallus gallus XP_001232435 1829 210000 R1107 S I D F T P L R S E E I Q L G
Frog Xenopus laevis Q6NRP2 1828 209984 E1108 S S Q L P H P E E L A L A I K
Zebra Danio Brachydanio rerio XP_002664015 1827 209361 E1106 T P H M G T P E D Q E L Q Q G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121383 1758 204045 E1072 T T L S Q P T E D E T I E S L
Nematode Worm Caenorhab. elegans NP_506153 1908 219794 T1172 D M L Q G P S T A E L E K Y K
Sea Urchin Strong. purpuratus XP_794837 1834 211775 Y1137 N Q S N M R V Y N E L V A E L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 93.8 N.A. 95.7 95.7 N.A. 88.2 86.4 83.8 77.3 N.A. N.A. 36.8 29.8 49.5
Protein Similarity: 100 N.A. N.A. 95.2 N.A. 97.8 97.7 N.A. 93.5 91.9 91.4 87.2 N.A. N.A. 56.1 48.3 67.2
P-Site Identity: 100 N.A. N.A. 66.6 N.A. 86.6 86.6 N.A. 73.3 40 6.6 6.6 N.A. N.A. 13.3 20 13.3
P-Site Similarity: 100 N.A. N.A. 80 N.A. 93.3 93.3 N.A. 86.6 60 13.3 53.3 N.A. N.A. 26.6 33.3 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 10 0 10 0 19 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 19 0 0 0 0 0 19 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 10 0 0 28 10 82 37 10 10 46 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 19 0 0 0 0 0 0 0 0 0 64 % G
% His: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 46 0 0 10 0 0 0 0 0 0 64 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 28 0 55 0 19 % K
% Leu: 0 0 19 10 0 37 55 0 0 10 19 19 0 19 19 % L
% Met: 0 10 0 10 10 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 19 10 0 0 0 0 10 0 0 0 0 0 0 % N
% Pro: 0 10 0 0 10 28 19 0 37 0 0 0 0 0 0 % P
% Gln: 0 10 10 55 10 0 0 0 0 10 0 0 19 10 0 % Q
% Arg: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % R
% Ser: 64 19 28 10 0 0 10 46 19 0 0 0 0 10 0 % S
% Thr: 19 10 0 0 37 10 10 10 0 0 10 0 0 0 0 % T
% Val: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _