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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSME4 All Species: 22.12
Human Site: S774 Identified Species: 48.67
UniProt: Q14997 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14997 NP_055429.2 1843 211334 S774 I Q W H V P S S E E V S F A F
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_531823 1774 204047 S705 I Q W H V P S S E E V A F A F
Cat Felis silvestris
Mouse Mus musculus Q5SSW2 1843 211178 S774 I Q W H V P S S E E V S F A F
Rat Rattus norvegicus NP_001020311 1843 211166 S774 I Q W H V P S S E E V S F A F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517136 1820 208596 P751 I Q W H V P S P D E V S F A Y
Chicken Gallus gallus XP_001232435 1829 210000 S760 I Q W H V P S S E E I N F A F
Frog Xenopus laevis Q6NRP2 1828 209984 A761 I K W H V P S A E E M D F A Y
Zebra Danio Brachydanio rerio XP_002664015 1827 209361 T759 I Q W H V P S T E E T A F V F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121383 1758 204045 I748 Y W G Q I L D I N A L K V K W
Nematode Worm Caenorhab. elegans NP_506153 1908 219794 Q824 P E W I I P T Q E S I D R A T
Sea Urchin Strong. purpuratus XP_794837 1834 211775 D726 V K W H I P S D D G V A C V K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 93.8 N.A. 95.7 95.7 N.A. 88.2 86.4 83.8 77.3 N.A. N.A. 36.8 29.8 49.5
Protein Similarity: 100 N.A. N.A. 95.2 N.A. 97.8 97.7 N.A. 93.5 91.9 91.4 87.2 N.A. N.A. 56.1 48.3 67.2
P-Site Identity: 100 N.A. N.A. 93.3 N.A. 100 100 N.A. 80 86.6 66.6 73.3 N.A. N.A. 0 26.6 33.3
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 93.3 100 93.3 86.6 N.A. N.A. 20 53.3 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 10 0 28 0 73 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 0 0 0 0 0 0 10 10 19 0 0 19 0 0 0 % D
% Glu: 0 10 0 0 0 0 0 0 73 73 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 73 0 55 % F
% Gly: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % G
% His: 0 0 0 82 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 73 0 0 10 28 0 0 10 0 0 19 0 0 0 0 % I
% Lys: 0 19 0 0 0 0 0 0 0 0 0 10 0 10 10 % K
% Leu: 0 0 0 0 0 10 0 0 0 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 0 0 10 0 0 0 % N
% Pro: 10 0 0 0 0 91 0 10 0 0 0 0 0 0 0 % P
% Gln: 0 64 0 10 0 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % R
% Ser: 0 0 0 0 0 0 82 46 0 10 0 37 0 0 0 % S
% Thr: 0 0 0 0 0 0 10 10 0 0 10 0 0 0 10 % T
% Val: 10 0 0 0 73 0 0 0 0 0 55 0 10 19 0 % V
% Trp: 0 10 91 0 0 0 0 0 0 0 0 0 0 0 10 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 19 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _