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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSME4 All Species: 27.58
Human Site: T1525 Identified Species: 60.67
UniProt: Q14997 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14997 NP_055429.2 1843 211334 T1525 S L P N T T P T I S P H V P E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_531823 1774 204047 T1456 S L P N T A P T A S P R V P E
Cat Felis silvestris
Mouse Mus musculus Q5SSW2 1843 211178 T1525 S L P N T A P T T S P C I P E
Rat Rattus norvegicus NP_001020311 1843 211166 T1525 S L P N T A P T T S P C I P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517136 1820 208596 T1502 S L P N T A P T K S P R V S E
Chicken Gallus gallus XP_001232435 1829 210000 T1511 S L P N T A A T K S P R V H E
Frog Xenopus laevis Q6NRP2 1828 209984 T1510 S L P N T A P T K S P H I S D
Zebra Danio Brachydanio rerio XP_002664015 1827 209361 T1509 A L P Y T L P T K S P H I A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121383 1758 204045 R1455 A N P F E N M R E R L S S I L
Nematode Worm Caenorhab. elegans NP_506153 1908 219794 S1578 P A V G T D P S L P K R L Q P
Sea Urchin Strong. purpuratus XP_794837 1834 211775 T1525 A W S R E N Q T S S P H R Q E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 93.8 N.A. 95.7 95.7 N.A. 88.2 86.4 83.8 77.3 N.A. N.A. 36.8 29.8 49.5
Protein Similarity: 100 N.A. N.A. 95.2 N.A. 97.8 97.7 N.A. 93.5 91.9 91.4 87.2 N.A. N.A. 56.1 48.3 67.2
P-Site Identity: 100 N.A. N.A. 80 N.A. 73.3 73.3 N.A. 73.3 66.6 66.6 60 N.A. N.A. 6.6 13.3 33.3
P-Site Similarity: 100 N.A. N.A. 80 N.A. 80 80 N.A. 73.3 66.6 80 73.3 N.A. N.A. 13.3 33.3 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 28 10 0 0 0 55 10 0 10 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 19 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 0 0 19 0 0 0 10 0 0 0 0 0 73 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 37 0 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 37 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 37 0 10 0 0 0 0 % K
% Leu: 0 73 0 0 0 10 0 0 10 0 10 0 10 0 10 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 64 0 19 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 82 0 0 0 73 0 0 10 82 0 0 37 10 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 0 19 0 % Q
% Arg: 0 0 0 10 0 0 0 10 0 10 0 37 10 0 0 % R
% Ser: 64 0 10 0 0 0 0 10 10 82 0 10 10 19 0 % S
% Thr: 0 0 0 0 82 10 0 82 19 0 0 0 0 0 0 % T
% Val: 0 0 10 0 0 0 0 0 0 0 0 0 37 0 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _