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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSME4 All Species: 27.88
Human Site: T562 Identified Species: 61.33
UniProt: Q14997 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14997 NP_055429.2 1843 211334 T562 F G L I E S S T L E Q T R E E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_531823 1774 204047 T493 F G L I E S S T L E Q T R E E
Cat Felis silvestris
Mouse Mus musculus Q5SSW2 1843 211178 T562 F G L I E S S T L E Q T R E E
Rat Rattus norvegicus NP_001020311 1843 211166 T562 F G L I E S S T L E Q T R E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517136 1820 208596 T539 F G L I E S S T L E Q T R E E
Chicken Gallus gallus XP_001232435 1829 210000 T548 F G L I E S S T L E Q T R E E
Frog Xenopus laevis Q6NRP2 1828 209984 A549 F A L I E S S A L E Q T R E E
Zebra Danio Brachydanio rerio XP_002664015 1827 209361 T547 F A L I D S S T L E Q T R E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121383 1758 204045 L558 S F I D H S S L E L V R L E N
Nematode Worm Caenorhab. elegans NP_506153 1908 219794 S612 A V G Q T A S S T S T H G S I
Sea Urchin Strong. purpuratus XP_794837 1834 211775 I514 N L I E A C S I E H I R S Q D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 93.8 N.A. 95.7 95.7 N.A. 88.2 86.4 83.8 77.3 N.A. N.A. 36.8 29.8 49.5
Protein Similarity: 100 N.A. N.A. 95.2 N.A. 97.8 97.7 N.A. 93.5 91.9 91.4 87.2 N.A. N.A. 56.1 48.3 67.2
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 100 100 86.6 86.6 N.A. N.A. 20 6.6 6.6
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 100 100 86.6 93.3 N.A. N.A. 26.6 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 19 0 0 10 10 0 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 0 10 64 0 0 0 19 73 0 0 0 82 73 % E
% Phe: 73 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 55 10 0 0 0 0 0 0 0 0 0 10 0 0 % G
% His: 0 0 0 0 10 0 0 0 0 10 0 10 0 0 0 % H
% Ile: 0 0 19 73 0 0 0 10 0 0 10 0 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 73 0 0 0 0 10 73 10 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 73 0 0 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 19 73 0 0 % R
% Ser: 10 0 0 0 0 82 100 10 0 10 0 0 10 10 0 % S
% Thr: 0 0 0 0 10 0 0 64 10 0 10 73 0 0 0 % T
% Val: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _