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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSME4
All Species:
34.24
Human Site:
Y1251
Identified Species:
75.33
UniProt:
Q14997
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14997
NP_055429.2
1843
211334
Y1251
P
D
N
H
W
L
H
Y
D
S
K
T
I
P
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531823
1774
204047
Y1182
P
D
N
H
W
L
H
Y
D
S
K
S
I
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q5SSW2
1843
211178
Y1251
P
D
N
H
W
L
H
Y
D
S
K
N
I
P
R
Rat
Rattus norvegicus
NP_001020311
1843
211166
Y1251
P
D
N
H
W
L
H
Y
D
S
K
N
I
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517136
1820
208596
Y1228
P
D
N
Q
W
L
H
Y
D
S
E
N
L
P
T
Chicken
Gallus gallus
XP_001232435
1829
210000
Y1237
L
D
N
Q
W
L
H
Y
D
S
R
S
L
P
K
Frog
Xenopus laevis
Q6NRP2
1828
209984
Y1236
P
D
N
Q
W
L
L
Y
D
S
S
N
L
P
N
Zebra Danio
Brachydanio rerio
XP_002664015
1827
209361
Y1236
P
G
N
D
W
L
Q
Y
H
S
E
S
L
P
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121383
1758
204045
Y1202
S
D
N
T
W
L
Q
Y
N
Y
E
T
R
P
L
Nematode Worm
Caenorhab. elegans
NP_506153
1908
219794
Y1304
T
D
N
R
C
M
M
Y
E
E
E
K
L
P
K
Sea Urchin
Strong. purpuratus
XP_794837
1834
211775
Y1248
P
D
N
K
W
T
Q
Y
Q
C
D
R
L
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93.8
N.A.
95.7
95.7
N.A.
88.2
86.4
83.8
77.3
N.A.
N.A.
36.8
29.8
49.5
Protein Similarity:
100
N.A.
N.A.
95.2
N.A.
97.8
97.7
N.A.
93.5
91.9
91.4
87.2
N.A.
N.A.
56.1
48.3
67.2
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
93.3
93.3
N.A.
66.6
60
60
46.6
N.A.
N.A.
46.6
26.6
40
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
93.3
93.3
N.A.
80
86.6
66.6
66.6
N.A.
N.A.
60
60
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
91
0
10
0
0
0
0
64
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
10
37
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
37
0
0
55
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
37
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
37
10
0
0
19
% K
% Leu:
10
0
0
0
0
82
10
0
0
0
0
0
55
0
10
% L
% Met:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
100
0
0
0
0
0
10
0
0
37
0
0
19
% N
% Pro:
73
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% P
% Gln:
0
0
0
28
0
0
28
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
10
10
10
0
37
% R
% Ser:
10
0
0
0
0
0
0
0
0
73
10
28
0
0
0
% S
% Thr:
10
0
0
10
0
10
0
0
0
0
0
19
0
0
19
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
91
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _