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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSME4
All Species:
31.82
Human Site:
Y694
Identified Species:
70
UniProt:
Q14997
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14997
NP_055429.2
1843
211334
Y694
D
G
R
K
L
L
L
Y
R
E
Q
L
V
K
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531823
1774
204047
Y625
D
G
K
K
L
L
L
Y
R
E
Q
L
V
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q5SSW2
1843
211178
Y694
D
G
K
K
L
L
L
Y
R
E
Q
L
V
K
I
Rat
Rattus norvegicus
NP_001020311
1843
211166
Y694
D
G
K
K
L
L
L
Y
R
E
Q
L
V
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517136
1820
208596
Y671
D
G
K
E
L
L
P
Y
K
E
Q
L
V
R
I
Chicken
Gallus gallus
XP_001232435
1829
210000
Y680
D
G
K
K
L
L
P
Y
R
E
Q
L
G
K
I
Frog
Xenopus laevis
Q6NRP2
1828
209984
Y681
D
G
E
K
L
L
P
Y
K
E
Q
L
V
Q
I
Zebra Danio
Brachydanio rerio
XP_002664015
1827
209361
Y679
D
G
E
K
L
L
P
Y
R
T
Q
L
V
Q
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121383
1758
204045
L676
R
L
L
H
A
M
L
L
L
S
A
I
V
H
T
Nematode Worm
Caenorhab. elegans
NP_506153
1908
219794
L750
N
W
H
L
V
E
T
L
M
D
L
V
M
P
L
Sea Urchin
Strong. purpuratus
XP_794837
1834
211775
Y646
P
S
E
V
V
L
T
Y
K
D
T
L
K
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93.8
N.A.
95.7
95.7
N.A.
88.2
86.4
83.8
77.3
N.A.
N.A.
36.8
29.8
49.5
Protein Similarity:
100
N.A.
N.A.
95.2
N.A.
97.8
97.7
N.A.
93.5
91.9
91.4
87.2
N.A.
N.A.
56.1
48.3
67.2
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
93.3
93.3
N.A.
66.6
80
73.3
73.3
N.A.
N.A.
13.3
0
26.6
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
93.3
86.6
86.6
80
N.A.
N.A.
26.6
40
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
73
0
0
0
0
0
0
0
0
19
0
0
0
0
0
% D
% Glu:
0
0
28
10
0
10
0
0
0
64
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
73
0
0
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
10
10
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
73
% I
% Lys:
0
0
46
64
0
0
0
0
28
0
0
0
10
55
0
% K
% Leu:
0
10
10
10
73
82
46
19
10
0
10
82
0
0
10
% L
% Met:
0
0
0
0
0
10
0
0
10
0
0
0
10
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
37
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
73
0
0
19
0
% Q
% Arg:
10
0
10
0
0
0
0
0
55
0
0
0
0
10
0
% R
% Ser:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
19
0
0
10
10
0
0
0
10
% T
% Val:
0
0
0
10
19
0
0
0
0
0
0
10
73
0
10
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _