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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CUL7 All Species: 16.97
Human Site: S914 Identified Species: 53.33
UniProt: Q14999 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14999 NP_055595.2 1698 191161 S914 V C G G D S T S S L H T E L N
Chimpanzee Pan troglodytes XP_001136655 1698 191188 S914 V C G G D S T S S L H T E L N
Rhesus Macaque Macaca mulatta XP_001088003 1810 203195 S1026 V C G G D S A S S L H T E L N
Dog Lupus familis XP_538928 1683 189926 N899 V F G G D S T N S L N T E L N
Cat Felis silvestris
Mouse Mus musculus Q8VE73 1689 192274 K893 V C G G N S I K S V N K E L N
Rat Rattus norvegicus XP_001056520 1696 193015 S895 V C G G D S I S S V N T E L N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508500 1587 174471 S912 V L G G D S I S S V N T E L N
Chicken Gallus gallus XP_419326 1368 150521 Q711 R D R G Q L L Q L F G K L N R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 91 88.2 N.A. 78 80.5 N.A. 48.2 41.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 92.3 92.5 N.A. 87.2 88.8 N.A. 62.1 53.8 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 80 N.A. 60 80 N.A. 73.3 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 93.3 N.A. 80 93.3 N.A. 86.6 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % A
% Cys: 0 63 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 13 0 0 75 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 88 0 0 % E
% Phe: 0 13 0 0 0 0 0 0 0 13 0 0 0 0 0 % F
% Gly: 0 0 88 100 0 0 0 0 0 0 13 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 38 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 38 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 13 0 0 0 25 0 0 0 % K
% Leu: 0 13 0 0 0 13 13 0 13 50 0 0 13 88 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 13 0 0 13 0 0 50 0 0 13 88 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 13 0 0 13 0 0 0 0 0 0 0 % Q
% Arg: 13 0 13 0 0 0 0 0 0 0 0 0 0 0 13 % R
% Ser: 0 0 0 0 0 88 0 63 88 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 38 0 0 0 0 75 0 0 0 % T
% Val: 88 0 0 0 0 0 0 0 0 38 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _