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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CUL7 All Species: 24.55
Human Site: Y1321 Identified Species: 77.14
UniProt: Q14999 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14999 NP_055595.2 1698 191161 Y1321 L Q R Q F H V Y Q L Q Q L D Q
Chimpanzee Pan troglodytes XP_001136655 1698 191188 Y1321 L Q R Q F H V Y Q L Q Q L D Q
Rhesus Macaque Macaca mulatta XP_001088003 1810 203195 Y1433 L Q R Q F H V Y Q L Q R L D Q
Dog Lupus familis XP_538928 1683 189926 Y1306 L Q R Q F H V Y Q L Q R L D Q
Cat Felis silvestris
Mouse Mus musculus Q8VE73 1689 192274 Y1300 L Q R Q F H V Y Q L Q Q L D Q
Rat Rattus norvegicus XP_001056520 1696 193015 Y1302 L Q R R F H V Y Q L Q Q L D Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508500 1587 174471 Y1265 F E H F Y R Y Y L G E R L L G
Chicken Gallus gallus XP_419326 1368 150521 C1057 V L V L S P R C W P V S P L C
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 91 88.2 N.A. 78 80.5 N.A. 48.2 41.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 92.3 92.5 N.A. 87.2 88.8 N.A. 62.1 53.8 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 93.3 N.A. 100 93.3 N.A. 13.3 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 40 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 13 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 75 0 % D
% Glu: 0 13 0 0 0 0 0 0 0 0 13 0 0 0 0 % E
% Phe: 13 0 0 13 75 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 13 % G
% His: 0 0 13 0 0 75 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 75 13 0 13 0 0 0 0 13 75 0 0 88 25 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 13 0 0 0 13 0 0 13 0 0 % P
% Gln: 0 75 0 63 0 0 0 0 75 0 75 50 0 0 75 % Q
% Arg: 0 0 75 13 0 13 13 0 0 0 0 38 0 0 0 % R
% Ser: 0 0 0 0 13 0 0 0 0 0 0 13 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 13 0 13 0 0 0 75 0 0 0 13 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 13 0 13 88 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _