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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHPRH
All Species:
16.06
Human Site:
S646
Identified Species:
35.33
UniProt:
Q149N8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q149N8
NP_001036148.1
1683
193079
S646
A
D
S
D
V
P
P
S
N
T
M
S
P
F
N
Chimpanzee
Pan troglodytes
XP_001172976
1683
193077
S646
A
D
S
D
V
P
P
S
N
T
M
S
P
F
N
Rhesus Macaque
Macaca mulatta
XP_001086512
1683
193033
S646
D
V
S
D
V
P
P
S
N
T
M
S
P
F
N
Dog
Lupus familis
XP_533438
1685
193077
S648
A
D
G
D
V
P
Q
S
T
I
L
S
P
C
N
Cat
Felis silvestris
Mouse
Mus musculus
Q7TPQ3
1674
191472
S637
A
A
E
E
L
A
Q
S
N
T
S
S
P
C
E
Rat
Rattus norvegicus
NP_001100940
1701
194686
S644
A
A
M
E
L
A
Q
S
N
T
A
S
F
C
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506895
1042
119725
N147
Y
V
D
I
P
H
S
N
S
E
D
G
R
R
F
Chicken
Gallus gallus
XP_419651
1681
192161
V648
S
V
Q
R
T
S
S
V
F
P
F
N
T
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648034
1270
148040
V375
G
L
H
S
T
F
W
V
S
P
F
D
L
A
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002329202
1320
149464
D426
C
V
C
G
A
V
S
D
S
Y
K
Y
R
G
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_181609
1664
188054
D658
F
L
K
A
N
P
F
D
V
S
R
W
W
I
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98
92.5
N.A.
86
84.6
N.A.
52.7
72
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.9
95.7
N.A.
91.8
90.7
N.A.
56.9
82.2
N.A.
N.A.
N.A.
42.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
60
N.A.
40
33.3
N.A.
0
0
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
66.6
N.A.
53.3
46.6
N.A.
13.3
13.3
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
20.9
N.A.
N.A.
20.8
N.A.
N.A.
Protein Similarity:
37.7
N.A.
N.A.
38.6
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
46
19
0
10
10
19
0
0
0
0
10
0
0
10
0
% A
% Cys:
10
0
10
0
0
0
0
0
0
0
0
0
0
28
0
% C
% Asp:
10
28
10
37
0
0
0
19
0
0
10
10
0
0
0
% D
% Glu:
0
0
10
19
0
0
0
0
0
10
0
0
0
0
37
% E
% Phe:
10
0
0
0
0
10
10
0
10
0
19
0
10
28
10
% F
% Gly:
10
0
10
10
0
0
0
0
0
0
0
10
0
10
0
% G
% His:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
10
0
0
0
10
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
19
0
0
19
0
0
0
0
0
10
0
10
0
10
% L
% Met:
0
0
10
0
0
0
0
0
0
0
28
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
10
46
0
0
10
0
0
37
% N
% Pro:
0
0
0
0
10
46
28
0
0
19
0
0
46
0
0
% P
% Gln:
0
0
10
0
0
0
28
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
10
0
19
10
0
% R
% Ser:
10
0
28
10
0
10
28
55
28
10
10
55
0
10
0
% S
% Thr:
0
0
0
0
19
0
0
0
10
46
0
0
10
0
0
% T
% Val:
0
37
0
0
37
10
0
19
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
10
10
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _