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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHPRH
All Species:
25.45
Human Site:
Y348
Identified Species:
56
UniProt:
Q149N8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q149N8
NP_001036148.1
1683
193079
Y348
S
E
G
L
K
L
Y
Y
N
P
Y
T
G
C
I
Chimpanzee
Pan troglodytes
XP_001172976
1683
193077
Y348
S
E
G
L
K
L
Y
Y
N
P
Y
T
G
C
I
Rhesus Macaque
Macaca mulatta
XP_001086512
1683
193033
Y348
S
E
G
L
K
L
Y
Y
N
P
Y
T
G
C
I
Dog
Lupus familis
XP_533438
1685
193077
Y350
P
E
D
L
K
L
Y
Y
N
P
Y
T
G
C
I
Cat
Felis silvestris
Mouse
Mus musculus
Q7TPQ3
1674
191472
Y343
P
D
G
L
K
L
Y
Y
N
P
Y
T
G
C
I
Rat
Rattus norvegicus
NP_001100940
1701
194686
Y341
P
D
G
L
N
L
Y
Y
N
P
Y
T
G
C
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506895
1042
119725
Chicken
Gallus gallus
XP_419651
1681
192161
Y351
L
D
G
V
K
I
Y
Y
N
P
F
T
G
C
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648034
1270
148040
G92
R
E
I
E
M
E
V
G
E
Q
V
L
P
L
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002329202
1320
149464
R143
K
S
M
V
E
E
D
R
E
V
E
S
V
I
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_181609
1664
188054
L337
D
S
A
T
K
M
F
L
N
P
F
S
G
N
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98
92.5
N.A.
86
84.6
N.A.
52.7
72
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.9
95.7
N.A.
91.8
90.7
N.A.
56.9
82.2
N.A.
N.A.
N.A.
42.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
80
N.A.
0
60
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
86.6
N.A.
0
93.3
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
20.9
N.A.
N.A.
20.8
N.A.
N.A.
Protein Similarity:
37.7
N.A.
N.A.
38.6
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
64
0
% C
% Asp:
10
28
10
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
46
0
10
10
19
0
0
19
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
19
0
0
0
19
% F
% Gly:
0
0
55
0
0
0
0
10
0
0
0
0
73
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
10
0
0
0
0
0
0
0
10
64
% I
% Lys:
10
0
0
0
64
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
55
0
55
0
10
0
0
0
10
0
10
0
% L
% Met:
0
0
10
0
10
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
73
0
0
0
0
10
0
% N
% Pro:
28
0
0
0
0
0
0
0
0
73
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
28
19
0
0
0
0
0
0
0
0
0
19
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
0
64
0
0
0
% T
% Val:
0
0
0
19
0
0
10
0
0
10
10
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
64
64
0
0
55
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _