KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM132D
All Species:
23.03
Human Site:
T790
Identified Species:
63.33
UniProt:
Q14C87
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14C87
NP_597705.2
1099
122309
T790
K
S
V
L
A
V
G
T
A
N
I
K
V
K
F
Chimpanzee
Pan troglodytes
XP_522557
1158
128168
V842
K
S
I
L
A
V
G
V
G
N
V
R
V
K
F
Rhesus Macaque
Macaca mulatta
XP_001107847
754
83540
S464
A
N
P
N
T
S
D
S
R
H
T
G
A
G
V
Dog
Lupus familis
XP_543358
1092
119795
T784
K
S
V
L
A
V
G
T
A
N
V
K
V
K
F
Cat
Felis silvestris
Mouse
Mus musculus
Q76HP3
1097
121397
T789
K
S
V
L
A
V
G
T
A
S
I
K
V
K
F
Rat
Rattus norvegicus
Q76HP2
1097
121260
T789
K
S
V
L
A
V
G
T
A
S
I
K
V
K
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508797
1090
121375
T781
K
S
V
L
A
V
G
T
G
N
I
K
V
K
F
Chicken
Gallus gallus
XP_415097
1090
121589
S782
K
S
I
L
A
V
G
S
G
S
I
K
V
K
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001332905
717
78633
A427
T
K
R
R
T
V
L
A
A
G
N
A
N
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.8
63.9
81.7
N.A.
83.1
83.2
N.A.
80.2
80.5
N.A.
36.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
72.1
66.3
90
N.A.
91.2
90.8
N.A.
89.4
90.3
N.A.
48.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
66.6
0
93.3
N.A.
93.3
93.3
N.A.
93.3
73.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
20
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
78
0
0
12
56
0
0
12
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
78
% F
% Gly:
0
0
0
0
0
0
78
0
34
12
0
12
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% H
% Ile:
0
0
23
0
0
0
0
0
0
0
56
0
0
0
0
% I
% Lys:
78
12
0
0
0
0
0
0
0
0
0
67
0
78
0
% K
% Leu:
0
0
0
78
0
0
12
0
0
0
0
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
12
0
0
0
0
0
45
12
0
12
0
0
% N
% Pro:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
12
12
0
0
0
0
12
0
0
12
0
0
0
% R
% Ser:
0
78
0
0
0
12
0
23
0
34
0
0
0
0
0
% S
% Thr:
12
0
0
0
23
0
0
56
0
0
12
0
0
0
0
% T
% Val:
0
0
56
0
0
89
0
12
0
0
23
0
78
12
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _