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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGAP19
All Species:
11.52
Human Site:
S412
Identified Species:
28.15
UniProt:
Q14CB8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14CB8
NP_116289.4
494
55756
S412
P
G
R
E
P
S
T
S
Q
V
Q
K
R
A
R
Chimpanzee
Pan troglodytes
XP_001161248
493
55609
S412
P
G
R
E
P
S
T
S
Q
V
Q
K
R
A
R
Rhesus Macaque
Macaca mulatta
XP_001101897
494
55652
S412
P
G
R
E
P
S
A
S
Q
V
Q
K
R
A
R
Dog
Lupus familis
XP_534979
517
58808
P412
P
G
R
E
S
S
T
P
W
V
Q
K
R
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRH3
494
55716
P412
P
G
R
E
P
S
T
P
R
V
Q
K
R
A
R
Rat
Rattus norvegicus
XP_001054615
479
54201
Q399
L
I
R
Q
F
H
K
Q
S
L
T
Q
T
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505449
583
65045
S504
A
Q
R
V
T
E
A
S
L
Q
E
P
S
S
R
Chicken
Gallus gallus
Q5F3G0
495
55431
P407
P
S
S
D
V
A
T
P
P
A
P
R
R
A
R
Frog
Xenopus laevis
Q6INE5
507
57385
P413
P
V
S
D
T
Q
V
P
N
G
K
K
H
V
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199994
277
31567
T199
R
L
R
A
T
R
T
T
S
Q
V
G
A
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.9
90.7
N.A.
87.8
83.8
N.A.
58.8
72.9
66
N.A.
N.A.
N.A.
N.A.
N.A.
23.8
Protein Similarity:
100
99.8
98.5
92.4
N.A.
93.1
88.8
N.A.
65.8
81.6
78.6
N.A.
N.A.
N.A.
N.A.
N.A.
34.8
P-Site Identity:
100
100
93.3
80
N.A.
86.6
6.6
N.A.
20
33.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
93.3
80
N.A.
93.3
26.6
N.A.
33.3
53.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
10
20
0
0
10
0
0
10
60
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
50
0
10
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
50
0
0
0
0
0
0
0
10
0
10
0
0
10
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
10
60
0
0
0
% K
% Leu:
10
10
0
0
0
0
0
0
10
10
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
70
0
0
0
40
0
0
40
10
0
10
10
0
10
0
% P
% Gln:
0
10
0
10
0
10
0
10
30
20
50
10
0
0
0
% Q
% Arg:
10
0
80
0
0
10
0
0
10
0
0
10
60
0
90
% R
% Ser:
0
10
20
0
10
50
0
40
20
0
0
0
10
10
0
% S
% Thr:
0
0
0
0
30
0
60
10
0
0
10
0
10
0
0
% T
% Val:
0
10
0
10
10
0
10
0
0
50
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _