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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGAP19
All Species:
13.64
Human Site:
T446
Identified Species:
33.33
UniProt:
Q14CB8
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14CB8
NP_116289.4
494
55756
T446
E
K
K
K
K
N
P
T
P
E
S
V
A
I
G
Chimpanzee
Pan troglodytes
XP_001161248
493
55609
P446
E
K
K
K
N
P
T
P
E
S
V
A
I
G
E
Rhesus Macaque
Macaca mulatta
XP_001101897
494
55652
T446
E
K
K
K
R
N
P
T
P
E
S
V
A
I
G
Dog
Lupus familis
XP_534979
517
58808
T446
E
K
K
N
K
Y
P
T
P
E
S
V
A
I
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRH3
494
55716
A446
E
K
K
N
S
S
P
A
P
E
S
V
A
M
G
Rat
Rattus norvegicus
XP_001054615
479
54201
G433
L
I
K
R
K
V
L
G
S
Q
M
T
S
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505449
583
65045
D538
D
L
K
N
L
Q
L
D
K
N
Q
I
S
C
I
Chicken
Gallus gallus
Q5F3G0
495
55431
T441
E
R
K
S
R
D
S
T
P
E
P
K
R
V
S
Frog
Xenopus laevis
Q6INE5
507
57385
T447
E
K
K
S
R
T
I
T
P
Q
S
A
D
G
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199994
277
31567
N233
L
L
H
T
V
A
A
N
E
E
T
N
K
M
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.9
90.7
N.A.
87.8
83.8
N.A.
58.8
72.9
66
N.A.
N.A.
N.A.
N.A.
N.A.
23.8
Protein Similarity:
100
99.8
98.5
92.4
N.A.
93.1
88.8
N.A.
65.8
81.6
78.6
N.A.
N.A.
N.A.
N.A.
N.A.
34.8
P-Site Identity:
100
26.6
93.3
86.6
N.A.
66.6
13.3
N.A.
6.6
33.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
100
86.6
N.A.
80
33.3
N.A.
26.6
60
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
10
10
0
0
0
20
40
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
10
0
0
0
0
10
0
10
0
0
0
0
10
0
0
% D
% Glu:
70
0
0
0
0
0
0
0
20
60
0
0
0
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
0
0
20
40
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
10
0
0
0
0
10
10
30
10
% I
% Lys:
0
60
90
30
30
0
0
0
10
0
0
10
10
0
10
% K
% Leu:
20
20
0
0
10
0
20
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
20
0
% M
% Asn:
0
0
0
30
10
20
0
10
0
10
0
10
0
0
10
% N
% Pro:
0
0
0
0
0
10
40
10
60
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
20
10
0
0
0
0
% Q
% Arg:
0
10
0
10
30
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
0
0
0
20
10
10
10
0
10
10
50
0
20
0
20
% S
% Thr:
0
0
0
10
0
10
10
50
0
0
10
10
0
0
0
% T
% Val:
0
0
0
0
10
10
0
0
0
0
10
40
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _