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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FASTKD3 All Species: 8.79
Human Site: S639 Identified Species: 21.48
UniProt: Q14CZ7 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14CZ7 NP_076996.2 662 75689 S639 H E I G M L K S R R E L V E Y
Chimpanzee Pan troglodytes XP_517625 645 73714 S622 H E I G M L K S R R E L V E Y
Rhesus Macaque Macaca mulatta XP_001103566 522 58260 P500 L E S Q R G L P Q L K S Y L R
Dog Lupus familis XP_545176 661 75120 K639 Y Y E I E V L K S R G E L V E
Cat Felis silvestris
Mouse Mus musculus Q8BSN9 661 75298 T639 Y H E L E L L T S R L E L V D
Rat Rattus norvegicus Q68FN9 656 75229 T634 Y H E L E L L T S R L E L V D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_419017 586 66775 K564 F F E V E S I K S C R K M A E
Frog Xenopus laevis Q6GQ66 832 95359 S805 Y H V L Q I S S L E W N S M E
Zebra Danio Brachydanio rerio XP_001338251 653 73406 K631 Y Y E F E K L K K K K E V V E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797262 955 107239 L869 F E W H S A E L A E P E D K L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.6 21.4 74.7 N.A. 64.6 68.4 N.A. N.A. 45.6 22.3 40.6 N.A. N.A. N.A. N.A. 20.4
Protein Similarity: 100 97.1 36.8 84.7 N.A. 79.4 81.1 N.A. N.A. 61.9 40.5 59.2 N.A. N.A. N.A. N.A. 36.5
P-Site Identity: 100 100 6.6 6.6 N.A. 13.3 13.3 N.A. N.A. 0 6.6 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 20 26.6 N.A. 33.3 33.3 N.A. N.A. 6.6 26.6 33.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 0 10 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 20 % D
% Glu: 0 40 50 0 50 0 10 0 0 20 20 50 0 20 40 % E
% Phe: 20 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 20 0 10 0 0 0 0 10 0 0 0 0 % G
% His: 20 30 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 20 10 0 10 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 20 30 10 10 20 10 0 10 0 % K
% Leu: 10 0 0 30 0 40 50 10 10 10 20 20 30 10 10 % L
% Met: 0 0 0 0 20 0 0 0 0 0 0 0 10 10 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 0 0 10 0 0 0 0 % P
% Gln: 0 0 0 10 10 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 10 0 0 0 20 50 10 0 0 0 10 % R
% Ser: 0 0 10 0 10 10 10 30 40 0 0 10 10 0 0 % S
% Thr: 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 % T
% Val: 0 0 10 10 0 10 0 0 0 0 0 0 30 40 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 50 20 0 0 0 0 0 0 0 0 0 0 10 0 20 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _