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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FASTKD3 All Species: 25.76
Human Site: Y420 Identified Species: 62.96
UniProt: Q14CZ7 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14CZ7 NP_076996.2 662 75689 Y420 E P F G K L N Y L P P N A S A
Chimpanzee Pan troglodytes XP_517625 645 73714 Y403 E P F G K L N Y L P P N A S A
Rhesus Macaque Macaca mulatta XP_001103566 522 58260 R304 Q L R C L P F R A L H F V F S
Dog Lupus familis XP_545176 661 75120 Y421 E P F G K L N Y L P P N A S T
Cat Felis silvestris
Mouse Mus musculus Q8BSN9 661 75298 Y421 E P F G K L N Y V P P N A P A
Rat Rattus norvegicus Q68FN9 656 75229 Y416 E P F G K L N Y L P P N A P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_419017 586 66775 T368 K L E A I L H T R L G Q F R P
Frog Xenopus laevis Q6GQ66 832 95359 Y571 L P F V V L N Y E P P N G E A
Zebra Danio Brachydanio rerio XP_001338251 653 73406 Y415 T T L G V L G Y L P P D A G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797262 955 107239 Y644 S P F S S L N Y K P K S T S D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.6 21.4 74.7 N.A. 64.6 68.4 N.A. N.A. 45.6 22.3 40.6 N.A. N.A. N.A. N.A. 20.4
Protein Similarity: 100 97.1 36.8 84.7 N.A. 79.4 81.1 N.A. N.A. 61.9 40.5 59.2 N.A. N.A. N.A. N.A. 36.5
P-Site Identity: 100 100 0 93.3 N.A. 86.6 93.3 N.A. N.A. 6.6 60 46.6 N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: 100 100 13.3 93.3 N.A. 93.3 93.3 N.A. N.A. 20 60 53.3 N.A. N.A. N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 10 0 0 0 60 0 50 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % D
% Glu: 50 0 10 0 0 0 0 0 10 0 0 0 0 10 0 % E
% Phe: 0 0 70 0 0 0 10 0 0 0 0 10 10 10 0 % F
% Gly: 0 0 0 60 0 0 10 0 0 0 10 0 10 10 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 50 0 0 0 10 0 10 0 0 0 0 % K
% Leu: 10 20 10 0 10 90 0 0 50 20 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 70 0 0 0 0 60 0 0 0 % N
% Pro: 0 70 0 0 0 10 0 0 0 80 70 0 0 20 10 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 0 0 10 0 0 0 0 10 10 0 0 0 0 10 10 % R
% Ser: 10 0 0 10 10 0 0 0 0 0 0 10 0 40 10 % S
% Thr: 10 10 0 0 0 0 0 10 0 0 0 0 10 0 10 % T
% Val: 0 0 0 10 20 0 0 0 10 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 80 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _