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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FASTKD3 All Species: 4.55
Human Site: Y646 Identified Species: 11.11
UniProt: Q14CZ7 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.56
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14CZ7 NP_076996.2 662 75689 Y646 S R R E L V E Y L Q R K L F S
Chimpanzee Pan troglodytes XP_517625 645 73714 Y629 S R R E L V E Y L Q R K L F S
Rhesus Macaque Macaca mulatta XP_001103566 522 58260 R507 P Q L K S Y L R Q K L Q A L G
Dog Lupus familis XP_545176 661 75120 E646 K S R G E L V E Y L Q R K L F
Cat Felis silvestris
Mouse Mus musculus Q8BSN9 661 75298 D646 T S R L E L V D Y L Q R K L F
Rat Rattus norvegicus Q68FN9 656 75229 D641 T S R L E L V D Y L Q R K L F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_419017 586 66775 E571 K S C R K M A E Y L H R K I F
Frog Xenopus laevis Q6GQ66 832 95359 E812 S L E W N S M E L S T K D A W
Zebra Danio Brachydanio rerio XP_001338251 653 73406 E638 K K K K E V V E Y L H K K I F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797262 955 107239 L876 L A E P E D K L Q Y L H E L L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.6 21.4 74.7 N.A. 64.6 68.4 N.A. N.A. 45.6 22.3 40.6 N.A. N.A. N.A. N.A. 20.4
Protein Similarity: 100 97.1 36.8 84.7 N.A. 79.4 81.1 N.A. N.A. 61.9 40.5 59.2 N.A. N.A. N.A. N.A. 36.5
P-Site Identity: 100 100 0 6.6 N.A. 6.6 6.6 N.A. N.A. 0 20 13.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 26.6 26.6 N.A. 33.3 33.3 N.A. N.A. 13.3 20 33.3 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 10 0 0 0 0 0 10 10 0 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 20 0 0 0 0 10 0 0 % D
% Glu: 0 0 20 20 50 0 20 40 0 0 0 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 50 % F
% Gly: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 20 10 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % I
% Lys: 30 10 10 20 10 0 10 0 0 10 0 40 50 0 0 % K
% Leu: 10 10 10 20 20 30 10 10 30 50 20 0 20 50 10 % L
% Met: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 0 0 0 0 0 20 20 30 10 0 0 0 % Q
% Arg: 0 20 50 10 0 0 0 10 0 0 20 40 0 0 0 % R
% Ser: 30 40 0 0 10 10 0 0 0 10 0 0 0 0 20 % S
% Thr: 20 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % T
% Val: 0 0 0 0 0 30 40 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % W
% Tyr: 0 0 0 0 0 10 0 20 50 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _