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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HEPACAM All Species: 9.09
Human Site: S364 Identified Species: 28.57
UniProt: Q14CZ8 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14CZ8 NP_689935.2 416 46026 S364 S A R R Y P R S P A R S P A T
Chimpanzee Pan troglodytes XP_522240 416 45990 S364 S A R R Y P R S P A R S P A T
Rhesus Macaque Macaca mulatta XP_001106985 546 60851 S494 S A R R Y P R S P A R S P A T
Dog Lupus familis XP_852267 418 45887 P364 I R S A R R Y P R S P A R S P
Cat Felis silvestris
Mouse Mus musculus Q640R3 418 46348 P364 I R S A R R Y P R S P A R S P
Rat Rattus norvegicus Q9JHY1 300 32351 L252 V T L I L L G L L I F G I W F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425793 386 42020 R337 S P G R G A R R Y H R S P A P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001018526 422 46573 V364 R R Y P R T P V P S P P P T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 73.4 93.5 N.A. 94.2 23 N.A. N.A. 66.8 N.A. 52.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 75 96.4 N.A. 96.6 35.8 N.A. N.A. 77.1 N.A. 68.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 0 N.A. 0 0 N.A. N.A. 46.6 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 20 N.A. 20 0 N.A. N.A. 46.6 N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 38 0 25 0 13 0 0 0 38 0 25 0 50 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 13 % F
% Gly: 0 0 13 0 13 0 13 0 0 0 0 13 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % H
% Ile: 25 0 0 13 0 0 0 0 0 13 0 0 13 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 13 0 13 13 0 13 13 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 13 0 13 0 38 13 25 50 0 38 13 63 0 50 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 13 38 38 50 38 25 50 13 25 0 50 0 25 0 0 % R
% Ser: 50 0 25 0 0 0 0 38 0 38 0 50 0 25 0 % S
% Thr: 0 13 0 0 0 13 0 0 0 0 0 0 0 13 38 % T
% Val: 13 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % W
% Tyr: 0 0 13 0 38 0 25 0 13 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _