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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VEPH1
All Species:
26.97
Human Site:
S449
Identified Species:
74.17
UniProt:
Q14D04
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14D04
NP_078897.1
833
94745
S449
I
R
F
N
R
S
K
S
L
A
F
H
T
M
L
Chimpanzee
Pan troglodytes
XP_001152820
833
94767
S449
I
R
F
N
R
S
K
S
L
A
F
H
T
M
L
Rhesus Macaque
Macaca mulatta
XP_001103348
833
94731
S449
I
R
F
N
R
S
K
S
L
A
L
H
T
V
L
Dog
Lupus familis
XP_542853
895
100754
S511
I
R
F
N
S
S
K
S
L
A
L
H
T
V
L
Cat
Felis silvestris
Mouse
Mus musculus
A1A535
833
94583
S449
I
R
F
S
R
S
R
S
L
A
L
N
T
V
L
Rat
Rattus norvegicus
Q5PQS3
832
94444
S449
V
R
F
S
R
S
R
S
L
A
L
N
T
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2BID5
813
91190
S452
M
R
F
N
R
S
K
S
L
A
L
H
A
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VS24
992
107890
T479
G
G
L
H
K
S
M
T
R
L
S
N
S
Q
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17237
871
97871
E476
S
D
I
N
E
S
R
E
L
S
M
I
S
M
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.5
80.3
N.A.
85.5
85.8
N.A.
N.A.
N.A.
N.A.
59
N.A.
31.8
N.A.
27.4
N.A.
Protein Similarity:
100
99.4
98.3
85.6
N.A.
91.4
91.5
N.A.
N.A.
N.A.
N.A.
73.8
N.A.
50.9
N.A.
47.6
N.A.
P-Site Identity:
100
100
86.6
80
N.A.
66.6
60
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
6.6
N.A.
26.6
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
80
N.A.
46.6
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
78
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
12
0
0
12
0
0
0
0
0
0
0
% E
% Phe:
0
0
78
0
0
0
0
0
0
0
23
0
0
0
0
% F
% Gly:
12
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
12
0
0
0
0
0
0
0
56
0
0
0
% H
% Ile:
56
0
12
0
0
0
0
0
0
0
0
12
0
0
12
% I
% Lys:
0
0
0
0
12
0
56
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
12
0
0
0
0
0
89
12
56
0
0
0
67
% L
% Met:
12
0
0
0
0
0
12
0
0
0
12
0
0
34
0
% M
% Asn:
0
0
0
67
0
0
0
0
0
0
0
34
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% Q
% Arg:
0
78
0
0
67
0
34
0
12
0
0
0
0
0
12
% R
% Ser:
12
0
0
23
12
100
0
78
0
12
12
0
23
0
0
% S
% Thr:
0
0
0
0
0
0
0
12
0
0
0
0
67
0
0
% T
% Val:
12
0
0
0
0
0
0
0
0
0
0
0
0
56
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _