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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NCAPH All Species: 13.94
Human Site: T729 Identified Species: 25.56
UniProt: Q15003 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15003 NP_056156.2 741 82563 T729 K N L K L E G T E D L S D V L
Chimpanzee Pan troglodytes XP_001148661 741 82518 T729 K N L K L E G T E D L S D V L
Rhesus Macaque Macaca mulatta XP_001097565 209 22886 E198 N L K L E G T E D L S D V L V
Dog Lupus familis XP_532948 916 102619 T772 L I G H L K Q T D L C T Y D L
Cat Felis silvestris
Mouse Mus musculus Q8C156 731 82284 T719 K N L K L E G T E D L S D V L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513175 869 95987 V857 K N L K L E G V E D L S D V R
Chicken Gallus gallus XP_001231605 383 41693 G372 E K I G E F V G N K S F T T V
Frog Xenopus laevis O13067 699 77759 D688 N L K L Q G M D D L S D V M I
Zebra Danio Brachydanio rerio NP_001073665 690 76324 I678 K N L E L H K I D G M T D I I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001187579 678 74012 A667 S L S L T V Q A E G L E D L L
Poplar Tree Populus trichocarpa XP_002321137 605 68469 A594 G L S I R G C A S L N D L S I
Maize Zea mays NP_001144998 674 75246 D663 R P M L D E I D I Y M P P T S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_180818 671 75347 S660 H N L S L I G S Q N L D D L T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 27.1 67.4 N.A. 77.8 N.A. N.A. 58 29 54.7 46.9 N.A. N.A. N.A. N.A. 35
Protein Similarity: 100 99.4 27.9 71.8 N.A. 83.8 N.A. N.A. 67 38.5 69.2 61.4 N.A. N.A. N.A. N.A. 50.6
P-Site Identity: 100 100 0 20 N.A. 100 N.A. N.A. 86.6 0 0 33.3 N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 100 20 40 N.A. 100 N.A. N.A. 86.6 20 20 73.3 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: 25.6 25.2 N.A. 23.7 N.A. N.A.
Protein Similarity: 43 41.8 N.A. 42.2 N.A. N.A.
P-Site Identity: 0 6.6 N.A. 40 N.A. N.A.
P-Site Similarity: 6.6 26.6 N.A. 66.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 16 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 16 31 31 0 31 54 8 0 % D
% Glu: 8 0 0 8 16 39 0 8 39 0 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 0 % F
% Gly: 8 0 8 8 0 24 39 8 0 16 0 0 0 0 0 % G
% His: 8 0 0 8 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 8 8 0 8 8 8 8 0 0 0 0 8 24 % I
% Lys: 39 8 16 31 0 8 8 0 0 8 0 0 0 0 0 % K
% Leu: 8 31 47 31 54 0 0 0 0 31 47 0 8 24 39 % L
% Met: 0 0 8 0 0 0 8 0 0 0 16 0 0 8 0 % M
% Asn: 16 47 0 0 0 0 0 0 8 8 8 0 0 0 0 % N
% Pro: 0 8 0 0 0 0 0 0 0 0 0 8 8 0 0 % P
% Gln: 0 0 0 0 8 0 16 0 8 0 0 0 0 0 0 % Q
% Arg: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 8 % R
% Ser: 8 0 16 8 0 0 0 8 8 0 24 31 0 8 8 % S
% Thr: 0 0 0 0 8 0 8 31 0 0 0 16 8 16 8 % T
% Val: 0 0 0 0 0 8 8 8 0 0 0 0 16 31 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _