KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPCS2
All Species:
29.7
Human Site:
S160
Identified Species:
54.44
UniProt:
Q15005
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15005
NP_055567.2
226
25003
S160
P
D
D
I
W
Q
L
S
S
S
L
K
R
F
D
Chimpanzee
Pan troglodytes
XP_001174940
226
24972
S160
P
D
D
I
W
Q
L
S
S
S
L
K
R
F
D
Rhesus Macaque
Macaca mulatta
XP_001101980
226
24979
S160
P
D
D
I
W
Q
L
S
S
S
L
K
R
F
D
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYN2
226
24959
S160
P
D
D
I
W
Q
L
S
S
S
L
K
R
F
D
Rat
Rattus norvegicus
XP_214994
226
24955
S160
P
D
D
I
W
Q
L
S
S
S
L
K
R
F
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518483
214
24573
S149
D
D
I
W
Q
L
S
S
S
L
K
R
F
D
D
Chicken
Gallus gallus
XP_417247
245
27821
N175
I
A
K
F
F
D
A
N
G
T
L
V
M
E
A
Frog
Xenopus laevis
NP_001092158
204
23364
S138
P
D
D
I
W
H
L
S
S
S
L
K
R
F
D
Zebra Danio
Brachydanio rerio
Q5BJI9
201
23091
S135
P
D
H
S
W
C
L
S
S
S
L
K
R
F
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYY2
199
22198
D134
S
S
D
M
R
K
Y
D
D
K
Y
L
L
T
L
Honey Bee
Apis mellifera
XP_393701
192
21282
S127
D
L
I
W
E
A
S
S
Y
L
K
R
Y
D
D
Nematode Worm
Caenorhab. elegans
Q9XWW1
180
20578
W115
D
G
K
Q
S
R
K
W
A
W
S
S
E
I
K
Sea Urchin
Strong. purpuratus
XP_796295
195
22496
S130
S
D
T
W
C
C
D
S
Y
M
K
R
F
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.2
N.A.
N.A.
95.5
95.1
N.A.
76.9
74.2
73
65
N.A.
34.9
46.9
31.4
41.5
Protein Similarity:
100
99.5
98.2
N.A.
N.A.
96.4
96
N.A.
81.8
79.5
83.1
78.7
N.A.
58.8
63.2
46.9
64.6
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
26.6
6.6
93.3
80
N.A.
6.6
13.3
0
20
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
33.3
26.6
93.3
80
N.A.
20
20
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
8
0
8
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
8
16
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
70
54
0
0
8
8
8
8
0
0
0
0
24
77
% D
% Glu:
0
0
0
0
8
0
0
0
0
0
0
0
8
8
0
% E
% Phe:
0
0
0
8
8
0
0
0
0
0
0
0
16
54
0
% F
% Gly:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
16
47
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
16
0
0
8
8
0
0
8
24
54
0
0
8
% K
% Leu:
0
8
0
0
0
8
54
0
0
16
62
8
8
0
8
% L
% Met:
0
0
0
8
0
0
0
0
0
8
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
54
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
8
39
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
8
0
0
0
0
0
24
54
0
0
% R
% Ser:
16
8
0
8
8
0
16
77
62
54
8
8
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
8
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
24
54
0
0
8
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
16
0
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _