KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPCS2
All Species:
20.3
Human Site:
S178
Identified Species:
37.22
UniProt:
Q15005
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15005
NP_055567.2
226
25003
S178
T
L
K
L
T
F
I
S
G
R
T
K
Q
Q
R
Chimpanzee
Pan troglodytes
XP_001174940
226
24972
S178
T
L
K
L
T
F
I
S
G
R
T
K
Q
Q
R
Rhesus Macaque
Macaca mulatta
XP_001101980
226
24979
S178
T
L
K
L
T
F
I
S
G
R
T
K
Q
Q
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYN2
226
24959
S178
T
L
K
L
T
F
I
S
G
R
T
K
Q
Q
R
Rat
Rattus norvegicus
XP_214994
226
24955
S178
T
L
K
L
T
F
I
S
G
R
T
K
Q
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518483
214
24573
G167
L
K
L
T
F
I
S
G
K
T
W
Q
Q
R
E
Chicken
Gallus gallus
XP_417247
245
27821
S193
E
V
S
K
L
H
D
S
L
A
L
E
R
K
T
Frog
Xenopus laevis
NP_001092158
204
23364
N156
T
L
K
V
T
Y
I
N
G
K
T
R
A
Y
R
Zebra Danio
Brachydanio rerio
Q5BJI9
201
23091
D153
T
L
R
M
S
F
T
D
G
K
T
K
Q
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYY2
199
22198
R152
D
T
K
N
G
K
R
R
E
Q
S
S
N
K
S
Honey Bee
Apis mellifera
XP_393701
192
21282
T145
L
V
L
S
V
R
S
T
A
T
G
N
V
N
E
Nematode Worm
Caenorhab. elegans
Q9XWW1
180
20578
E133
D
K
Y
T
L
S
A
E
F
K
K
E
G
R
S
Sea Urchin
Strong. purpuratus
XP_796295
195
22496
G148
L
V
L
Q
F
E
D
G
K
T
K
E
K
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.2
N.A.
N.A.
95.5
95.1
N.A.
76.9
74.2
73
65
N.A.
34.9
46.9
31.4
41.5
Protein Similarity:
100
99.5
98.2
N.A.
N.A.
96.4
96
N.A.
81.8
79.5
83.1
78.7
N.A.
58.8
63.2
46.9
64.6
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
6.6
6.6
53.3
53.3
N.A.
6.6
0
0
0
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
20
33.3
86.6
80
N.A.
26.6
13.3
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
8
8
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
0
0
0
16
8
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
8
0
8
8
0
0
24
0
0
24
% E
% Phe:
0
0
0
0
16
47
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
16
54
0
8
0
8
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
47
0
0
0
0
0
0
0
0
% I
% Lys:
0
16
54
8
0
8
0
0
16
24
16
47
8
16
0
% K
% Leu:
24
54
24
39
16
0
0
0
8
0
8
0
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
8
0
0
0
8
8
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
8
0
8
54
39
0
% Q
% Arg:
0
0
8
0
0
8
8
8
0
39
0
8
8
24
54
% R
% Ser:
0
0
8
8
8
8
16
47
0
0
8
8
0
8
16
% S
% Thr:
54
8
0
16
47
0
8
8
0
24
54
0
0
0
8
% T
% Val:
0
24
0
8
8
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
8
0
0
8
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _