KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPCS2
All Species:
19.09
Human Site:
S63
Identified Species:
35
UniProt:
Q15005
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15005
NP_055567.2
226
25003
S63
V
K
N
S
L
D
D
S
A
K
K
V
L
L
E
Chimpanzee
Pan troglodytes
XP_001174940
226
24972
S63
V
K
N
S
L
D
D
S
A
K
K
V
L
L
E
Rhesus Macaque
Macaca mulatta
XP_001101980
226
24979
S63
V
K
N
S
L
D
D
S
A
K
K
V
L
L
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYN2
226
24959
S63
V
K
N
S
L
D
D
S
A
K
K
V
L
L
E
Rat
Rattus norvegicus
XP_214994
226
24955
S63
V
K
N
S
L
D
D
S
A
K
K
V
L
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518483
214
24573
A52
K
N
S
L
D
D
S
A
K
K
I
L
L
E
K
Chicken
Gallus gallus
XP_417247
245
27821
Y78
I
V
A
L
I
W
D
Y
L
H
P
F
P
E
S
Frog
Xenopus laevis
NP_001092158
204
23364
A41
V
K
N
S
L
D
D
A
A
K
K
V
L
L
E
Zebra Danio
Brachydanio rerio
Q5BJI9
201
23091
A38
V
K
N
S
L
D
D
A
A
K
K
V
L
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYY2
199
22198
L37
D
D
A
V
K
T
C
L
L
G
D
R
P
Q
L
Honey Bee
Apis mellifera
XP_393701
192
21282
V30
K
N
A
L
D
D
A
V
K
D
V
L
T
K
K
Nematode Worm
Caenorhab. elegans
Q9XWW1
180
20578
K18
K
W
D
G
P
T
V
K
N
A
L
D
E
V
V
Sea Urchin
Strong. purpuratus
XP_796295
195
22496
I33
K
N
A
L
D
D
D
I
R
R
I
F
T
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.2
N.A.
N.A.
95.5
95.1
N.A.
76.9
74.2
73
65
N.A.
34.9
46.9
31.4
41.5
Protein Similarity:
100
99.5
98.2
N.A.
N.A.
96.4
96
N.A.
81.8
79.5
83.1
78.7
N.A.
58.8
63.2
46.9
64.6
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
20
6.6
93.3
86.6
N.A.
0
6.6
0
13.3
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
46.6
20
100
100
N.A.
0
20
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
31
0
0
0
8
24
54
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
0
24
77
70
0
0
8
8
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
8
16
54
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
0
0
0
8
0
0
8
0
0
16
0
0
8
0
% I
% Lys:
31
54
0
0
8
0
0
8
16
62
54
0
0
16
16
% K
% Leu:
0
0
0
31
54
0
0
8
16
0
8
16
62
47
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
24
54
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
8
0
16
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
8
0
8
0
0
0
% R
% Ser:
0
0
8
54
0
0
8
39
0
0
0
0
0
0
8
% S
% Thr:
0
0
0
0
0
16
0
0
0
0
0
0
16
0
0
% T
% Val:
54
8
0
8
0
0
8
8
0
0
8
54
0
8
16
% V
% Trp:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _