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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPCS2
All Species:
27.58
Human Site:
Y170
Identified Species:
50.56
UniProt:
Q15005
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15005
NP_055567.2
226
25003
Y170
L
K
R
F
D
D
K
Y
T
L
K
L
T
F
I
Chimpanzee
Pan troglodytes
XP_001174940
226
24972
Y170
L
K
R
F
D
D
K
Y
T
L
K
L
T
F
I
Rhesus Macaque
Macaca mulatta
XP_001101980
226
24979
Y170
L
K
R
F
D
D
K
Y
T
L
K
L
T
F
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYN2
226
24959
Y170
L
K
R
F
D
D
K
Y
T
L
K
L
T
F
I
Rat
Rattus norvegicus
XP_214994
226
24955
Y170
L
K
R
F
D
D
K
Y
T
L
K
L
T
F
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518483
214
24573
T159
K
R
F
D
D
K
Y
T
L
K
L
T
F
I
S
Chicken
Gallus gallus
XP_417247
245
27821
P185
L
V
M
E
A
Y
E
P
E
V
S
K
L
H
D
Frog
Xenopus laevis
NP_001092158
204
23364
Y148
L
K
R
F
D
D
K
Y
T
L
K
V
T
Y
I
Zebra Danio
Brachydanio rerio
Q5BJI9
201
23091
Y145
L
K
R
F
D
D
Q
Y
T
L
R
M
S
F
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYY2
199
22198
R144
Y
L
L
T
L
S
V
R
D
T
K
N
G
K
R
Honey Bee
Apis mellifera
XP_393701
192
21282
N137
K
R
Y
D
D
K
Y
N
L
V
L
S
V
R
S
Nematode Worm
Caenorhab. elegans
Q9XWW1
180
20578
D125
S
S
E
I
K
A
H
D
D
K
Y
T
L
S
A
Sea Urchin
Strong. purpuratus
XP_796295
195
22496
N140
K
R
F
D
D
E
Y
N
L
V
L
Q
F
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.2
N.A.
N.A.
95.5
95.1
N.A.
76.9
74.2
73
65
N.A.
34.9
46.9
31.4
41.5
Protein Similarity:
100
99.5
98.2
N.A.
N.A.
96.4
96
N.A.
81.8
79.5
83.1
78.7
N.A.
58.8
63.2
46.9
64.6
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
6.6
6.6
86.6
66.6
N.A.
6.6
6.6
0
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
13.3
20
100
93.3
N.A.
6.6
20
0
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
24
77
54
0
8
16
0
0
0
0
0
16
% D
% Glu:
0
0
8
8
0
8
8
0
8
0
0
0
0
8
0
% E
% Phe:
0
0
16
54
0
0
0
0
0
0
0
0
16
47
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
47
% I
% Lys:
24
54
0
0
8
16
47
0
0
16
54
8
0
8
0
% K
% Leu:
62
8
8
0
8
0
0
0
24
54
24
39
16
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
16
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% Q
% Arg:
0
24
54
0
0
0
0
8
0
0
8
0
0
8
8
% R
% Ser:
8
8
0
0
0
8
0
0
0
0
8
8
8
8
16
% S
% Thr:
0
0
0
8
0
0
0
8
54
8
0
16
47
0
8
% T
% Val:
0
8
0
0
0
0
8
0
0
24
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
8
24
54
0
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _