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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPCS2
All Species:
22.73
Human Site:
Y208
Identified Species:
41.67
UniProt:
Q15005
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15005
NP_055567.2
226
25003
Y208
G
T
L
V
M
D
A
Y
E
P
E
I
S
R
L
Chimpanzee
Pan troglodytes
XP_001174940
226
24972
Y208
G
T
L
V
M
D
A
Y
E
P
E
I
S
R
L
Rhesus Macaque
Macaca mulatta
XP_001101980
226
24979
Y208
G
T
L
V
M
D
A
Y
E
P
E
I
S
R
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYN2
226
24959
Y208
G
T
L
V
M
D
A
Y
E
P
E
I
S
R
L
Rat
Rattus norvegicus
XP_214994
226
24955
Y208
G
T
L
V
M
D
A
Y
E
P
E
I
S
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518483
214
24573
E197
M
L
V
M
E
T
Y
E
P
E
I
S
K
L
H
Chicken
Gallus gallus
XP_417247
245
27821
S223
V
S
D
C
V
F
L
S
R
C
T
M
G
P
A
Frog
Xenopus laevis
NP_001092158
204
23364
F186
G
T
L
V
M
D
L
F
E
P
E
V
S
K
L
Zebra Danio
Brachydanio rerio
Q5BJI9
201
23091
Y183
G
T
L
V
M
D
Q
Y
E
K
Y
V
S
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYY2
199
22198
L182
V
A
N
E
V
N
R
L
F
N
A
L
A
A
D
Honey Bee
Apis mellifera
XP_393701
192
21282
E175
V
V
I
P
E
L
I
E
N
V
V
T
N
M
H
Nematode Worm
Caenorhab. elegans
Q9XWW1
180
20578
L163
D
G
E
I
I
V
P
L
V
K
K
E
V
D
D
Sea Urchin
Strong. purpuratus
XP_796295
195
22496
Q178
L
L
L
H
E
L
F
Q
N
D
V
C
K
L
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.2
N.A.
N.A.
95.5
95.1
N.A.
76.9
74.2
73
65
N.A.
34.9
46.9
31.4
41.5
Protein Similarity:
100
99.5
98.2
N.A.
N.A.
96.4
96
N.A.
81.8
79.5
83.1
78.7
N.A.
58.8
63.2
46.9
64.6
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
0
0
73.3
66.6
N.A.
0
0
0
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
13.3
20
93.3
80
N.A.
26.6
13.3
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
39
0
0
0
8
0
8
8
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
8
0
8
0
0
0
% C
% Asp:
8
0
8
0
0
54
0
0
0
8
0
0
0
8
16
% D
% Glu:
0
0
8
8
24
0
0
16
54
8
47
8
0
0
0
% E
% Phe:
0
0
0
0
0
8
8
8
8
0
0
0
0
0
0
% F
% Gly:
54
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
24
% H
% Ile:
0
0
8
8
8
0
8
0
0
0
8
39
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
16
8
0
16
16
0
% K
% Leu:
8
16
62
0
0
16
16
16
0
0
0
8
0
16
54
% L
% Met:
8
0
0
8
54
0
0
0
0
0
0
8
0
8
0
% M
% Asn:
0
0
8
0
0
8
0
0
16
8
0
0
8
0
0
% N
% Pro:
0
0
0
8
0
0
8
0
8
47
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
8
0
0
0
0
39
0
% R
% Ser:
0
8
0
0
0
0
0
8
0
0
0
8
54
0
0
% S
% Thr:
0
54
0
0
0
8
0
0
0
0
8
8
0
0
0
% T
% Val:
24
8
8
54
16
8
0
0
8
8
16
16
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
47
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _