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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPCS2
All Species:
26.36
Human Site:
Y72
Identified Species:
48.33
UniProt:
Q15005
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15005
NP_055567.2
226
25003
Y72
K
K
V
L
L
E
K
Y
K
Y
V
E
N
F
G
Chimpanzee
Pan troglodytes
XP_001174940
226
24972
Y72
K
K
V
L
L
E
K
Y
K
Y
V
E
N
F
G
Rhesus Macaque
Macaca mulatta
XP_001101980
226
24979
Y72
K
K
V
L
L
E
K
Y
K
Y
V
E
N
F
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYN2
226
24959
Y72
K
K
V
L
L
E
K
Y
K
Y
V
E
N
F
G
Rat
Rattus norvegicus
XP_214994
226
24955
Y72
K
K
V
L
L
E
K
Y
K
Y
V
E
N
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518483
214
24573
K61
K
I
L
L
E
K
Y
K
Y
V
E
N
F
C
L
Chicken
Gallus gallus
XP_417247
245
27821
P87
H
P
F
P
E
S
K
P
V
L
A
F
C
V
V
Frog
Xenopus laevis
NP_001092158
204
23364
Y50
K
K
V
L
L
E
K
Y
R
Y
V
E
N
F
C
Zebra Danio
Brachydanio rerio
Q5BJI9
201
23091
Y47
K
K
V
L
I
E
K
Y
G
Y
L
E
S
F
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYY2
199
22198
E46
G
D
R
P
Q
L
K
E
Q
F
G
L
V
N
T
Honey Bee
Apis mellifera
XP_393701
192
21282
N39
D
V
L
T
K
K
Y
N
Y
I
E
N
F
A
L
Nematode Worm
Caenorhab. elegans
Q9XWW1
180
20578
K27
A
L
D
E
V
V
K
K
I
L
N
D
K
V
G
Sea Urchin
Strong. purpuratus
XP_796295
195
22496
E42
R
I
F
T
K
V
F
E
Y
D
E
N
H
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.2
N.A.
N.A.
95.5
95.1
N.A.
76.9
74.2
73
65
N.A.
34.9
46.9
31.4
41.5
Protein Similarity:
100
99.5
98.2
N.A.
N.A.
96.4
96
N.A.
81.8
79.5
83.1
78.7
N.A.
58.8
63.2
46.9
64.6
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
13.3
6.6
86.6
66.6
N.A.
6.6
0
13.3
0
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
26.6
6.6
93.3
86.6
N.A.
20
13.3
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
8
% C
% Asp:
8
8
8
0
0
0
0
0
0
8
0
8
0
0
0
% D
% Glu:
0
0
0
8
16
54
0
16
0
0
24
54
0
0
0
% E
% Phe:
0
0
16
0
0
0
8
0
0
8
0
8
16
54
0
% F
% Gly:
8
0
0
0
0
0
0
0
8
0
8
0
0
0
47
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
16
0
0
8
0
0
0
8
8
0
0
0
0
0
% I
% Lys:
62
54
0
0
16
16
77
16
39
0
0
0
8
0
0
% K
% Leu:
0
8
16
62
47
8
0
0
0
16
8
8
0
0
24
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
8
24
47
8
8
% N
% Pro:
0
8
0
16
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
8
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
0
0
0
0
0
8
8
0
% S
% Thr:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
8
% T
% Val:
0
8
54
0
8
16
0
0
8
8
47
0
8
16
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
16
54
24
54
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _