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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC35
All Species:
38.48
Human Site:
S241
Identified Species:
70.56
UniProt:
Q15006
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15006
NP_055488.1
297
34834
S241
M
S
A
S
H
I
A
S
N
P
K
A
S
A
K
Chimpanzee
Pan troglodytes
XP_001135662
306
35957
S250
M
S
A
S
H
I
A
S
N
P
K
A
S
A
K
Rhesus Macaque
Macaca mulatta
XP_001090826
297
34801
S241
M
S
A
S
H
I
A
S
N
P
K
A
S
A
K
Dog
Lupus familis
XP_853015
306
35814
S241
M
S
A
S
H
I
A
S
N
P
K
A
S
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CRD2
297
34916
S241
M
S
A
S
H
I
A
S
N
P
K
A
S
A
K
Rat
Rattus norvegicus
B0BNG0
297
34851
S241
M
S
A
S
H
I
A
S
N
P
K
A
S
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518300
323
37978
S267
M
S
A
S
H
I
A
S
N
P
K
A
S
A
K
Chicken
Gallus gallus
XP_418385
297
34866
S241
M
S
A
S
H
I
A
S
N
P
K
A
S
A
K
Frog
Xenopus laevis
Q6INS3
297
34576
S241
I
S
S
V
H
I
A
S
N
P
K
A
S
A
K
Zebra Danio
Brachydanio rerio
Q6TGY8
297
34438
A241
M
S
A
S
H
I
A
A
S
P
K
V
S
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650581
282
32742
A226
L
N
P
H
N
L
R
A
L
Y
G
I
Y
L
C
Honey Bee
Apis mellifera
XP_395349
289
33784
S234
L
Y
G
L
L
L
A
S
N
N
I
A
T
S
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786507
275
31958
K218
E
C
M
E
I
A
R
K
Y
F
A
H
A
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
99.6
89.5
N.A.
97.3
96.6
N.A.
88.8
96.3
85.1
85.1
N.A.
43.4
46.7
N.A.
51.8
Protein Similarity:
100
97
100
92.1
N.A.
98.9
98.6
N.A.
90.7
97.9
94.2
92.9
N.A.
69.3
72
N.A.
69.3
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
80
80
N.A.
0
26.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
93.3
93.3
N.A.
33.3
53.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
70
0
0
8
85
16
0
0
8
77
8
77
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
8
77
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
8
0
0
0
8
77
0
0
0
0
8
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
77
0
0
0
85
% K
% Leu:
16
0
0
8
8
16
0
0
8
0
0
0
0
8
0
% L
% Met:
70
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
0
77
8
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
77
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% R
% Ser:
0
77
8
70
0
0
0
77
8
0
0
0
77
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
8
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _