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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC35
All Species:
37.27
Human Site:
S281
Identified Species:
68.33
UniProt:
Q15006
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15006
NP_055488.1
297
34834
S281
S
K
K
E
T
K
Y
S
L
K
A
V
E
D
M
Chimpanzee
Pan troglodytes
XP_001135662
306
35957
S290
S
K
K
E
T
K
Y
S
L
K
A
V
E
D
M
Rhesus Macaque
Macaca mulatta
XP_001090826
297
34801
S281
S
K
K
E
T
K
Y
S
L
K
A
V
E
D
M
Dog
Lupus familis
XP_853015
306
35814
S281
F
T
L
S
N
Q
D
S
T
I
E
A
N
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CRD2
297
34916
S281
S
K
K
E
T
K
Y
S
L
K
A
V
E
D
M
Rat
Rattus norvegicus
B0BNG0
297
34851
S281
S
K
K
E
T
K
S
S
L
K
A
V
E
D
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518300
323
37978
S307
S
K
K
E
T
K
Y
S
L
K
A
V
E
D
M
Chicken
Gallus gallus
XP_418385
297
34866
S281
S
K
K
E
T
K
Y
S
L
K
A
V
E
D
M
Frog
Xenopus laevis
Q6INS3
297
34576
S281
T
M
T
D
T
Q
T
S
L
K
A
V
E
D
M
Zebra Danio
Brachydanio rerio
Q6TGY8
297
34438
S281
G
K
K
E
N
K
C
S
V
K
A
V
E
E
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650581
282
32742
T266
E
Q
L
L
T
K
Q
T
I
V
P
L
E
A
A
Honey Bee
Apis mellifera
XP_395349
289
33784
N274
Q
S
K
V
T
D
E
N
I
K
T
L
E
G
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786507
275
31958
N258
S
G
K
I
K
K
D
N
M
K
Y
A
S
W
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
99.6
89.5
N.A.
97.3
96.6
N.A.
88.8
96.3
85.1
85.1
N.A.
43.4
46.7
N.A.
51.8
Protein Similarity:
100
97
100
92.1
N.A.
98.9
98.6
N.A.
90.7
97.9
94.2
92.9
N.A.
69.3
72
N.A.
69.3
P-Site Identity:
100
100
100
6.6
N.A.
100
93.3
N.A.
100
100
60
66.6
N.A.
20
26.6
N.A.
26.6
P-Site Similarity:
100
100
100
20
N.A.
100
93.3
N.A.
100
100
80
80
N.A.
46.6
53.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
70
16
0
8
16
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
8
16
0
0
0
0
0
0
62
0
% D
% Glu:
8
0
0
62
0
0
8
0
0
0
8
0
85
8
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
0
0
0
0
0
0
0
0
0
0
0
16
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
16
8
0
0
0
0
0
% I
% Lys:
0
62
77
0
8
77
0
0
0
85
0
0
0
0
0
% K
% Leu:
0
0
16
8
0
0
0
0
62
0
0
16
0
0
16
% L
% Met:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
70
% M
% Asn:
0
0
0
0
16
0
0
16
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
8
8
0
0
0
16
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
62
8
0
8
0
0
8
77
0
0
0
0
8
0
0
% S
% Thr:
8
8
8
0
77
0
8
8
8
0
8
0
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
8
8
0
70
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
47
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _