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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WTAP All Species: 25.45
Human Site: S257 Identified Species: 46.67
UniProt: Q15007 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15007 NP_004897.2 396 44244 S257 S T S R T T A S E P V E Q S E
Chimpanzee Pan troglodytes XP_518837 396 44211 S257 S T S R T T A S E P V E Q S E
Rhesus Macaque Macaca mulatta XP_001096785 396 44278 S257 S T S R T T A S E P V E Q L E
Dog Lupus familis XP_533464 396 44153 S257 S T S R T T S S E P V G Q A E
Cat Felis silvestris
Mouse Mus musculus Q9ER69 396 44158 S257 S T S R T T S S E P V D Q A E
Rat Rattus norvegicus NP_001107014 395 44103 S257 S T S R T T S S E P V D Q A E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510041 305 32623 E167 S E P A E Q G E A L G K D C S
Chicken Gallus gallus XP_419626 396 44342 S257 G T S R T P S S E P T D Q G E
Frog Xenopus laevis Q4KLT6 393 44276 E254 G N R T P S S E P K D E G E T
Zebra Danio Brachydanio rerio Q7SXL7 423 46133 N275 P A N A S S S N V G K D C G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9Y091 536 59250 P320 I K D E V V A P A A A T N G G
Honey Bee Apis mellifera XP_625211 467 52898 N284 S S E N N L T N G L S P H T P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785342 681 75462 D283 L T P V S S A D M K H E Q Q I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.4 96.2 N.A. 96.4 96.4 N.A. 59.3 91.6 83.5 74.9 N.A. 31.7 34.6 N.A. 28.4
Protein Similarity: 100 100 99.7 97.7 N.A. 98.2 98.2 N.A. 63.6 94.4 90.6 82.5 N.A. 46 50.7 N.A. 39.9
P-Site Identity: 100 100 93.3 80 N.A. 80 80 N.A. 6.6 60 6.6 0 N.A. 6.6 6.6 N.A. 26.6
P-Site Similarity: 100 100 93.3 93.3 N.A. 100 100 N.A. 13.3 73.3 20 40 N.A. 6.6 26.6 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 16 0 0 39 0 16 8 8 0 0 24 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % C
% Asp: 0 0 8 0 0 0 0 8 0 0 8 31 8 0 0 % D
% Glu: 0 8 8 8 8 0 0 16 54 0 0 39 0 8 54 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 16 0 0 0 0 0 8 0 8 8 8 8 8 24 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % I
% Lys: 0 8 0 0 0 0 0 0 0 16 8 8 0 0 0 % K
% Leu: 8 0 0 0 0 8 0 0 0 16 0 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 8 8 8 8 0 0 16 0 0 0 0 8 0 0 % N
% Pro: 8 0 16 0 8 8 0 8 8 54 0 8 0 0 8 % P
% Gln: 0 0 0 0 0 8 0 0 0 0 0 0 62 8 0 % Q
% Arg: 0 0 8 54 0 0 0 0 0 0 0 0 0 0 8 % R
% Ser: 62 8 54 0 16 24 47 54 0 0 8 0 0 16 8 % S
% Thr: 0 62 0 8 54 47 8 0 0 0 8 8 0 8 8 % T
% Val: 0 0 0 8 8 8 0 0 8 0 47 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _